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  3. (rac)-Streptonigrin

(rac)-Streptonigrin  (Synonyms: (rac)-Bruneomycin)

Cat. No.: HY-124586A
Handling Instructions

(rac)-Streptonigrin ((rac)-Bruneomycin) is the racemic form of Streptonigrin. Streptonigrin (HY-124586) is a natural product produced by the actinobacterium Streptomyces flocculus, exhibiting antitumor and antibacterial activities. Streptonigrin can act as a pan-PAD inhibitor, with IC50 values of 48.3 μM, 26.1 μM, 0.43 μM, and 2.5 μM for PAD1, PAD2, PAD3, and PAD4, respectively.

For research use only. We do not sell to patients.

(rac)-Streptonigrin Chemical Structure

(rac)-Streptonigrin Chemical Structure

CAS No. : 1079893-79-0

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Description

(rac)-Streptonigrin ((rac)-Bruneomycin) is the racemic form of Streptonigrin. Streptonigrin (HY-124586) is a natural product produced by the actinobacterium Streptomyces flocculus, exhibiting antitumor and antibacterial activities. Streptonigrin can act as a pan-PAD inhibitor, with IC50 values of 48.3 μM, 26.1 μM, 0.43 μM, and 2.5 μM for PAD1, PAD2, PAD3, and PAD4, respectively[1].

Molecular Weight

506.46

Formula

C25H22N4O8

CAS No.
SMILES

O=C(C1=NC(C(N=C2C(C(N)=C3OC)=O)=CC=C2C3=O)=C(C(C4=CC=C(C(OC)=C4O)OC)=C1C)N)O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(rac)-Streptonigrin
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