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TLR7 agonist 13

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-154361
    TLR7 agonist 13

    		Nucleoside Antimetabolite/Analog Cancer
    TLR7 agonist 13 is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . TLR7 agonist 13 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    TLR7 agonist 13

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