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Tafluprost

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0600
    Tafluprost

    AFP-168; MK2452

    		 Apoptosis Cardiovascular Disease Others
    Tafluprost (AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Tafluprost can inhibit the apoptosis of retinal ganglion cells (RGCs) and rat RGCs cells. Tafluprost promotes axon regeneration by regulating Zn 2+-mTORpathway, inhibits intracellular lipid accumulation in human preorbital adipocytes. Tafluprost can be used in the study of optic nerve injury in glaucoma .
    Tafluprost
  • HY-139420
    Tafluprost ethyl amide

    		Others Others
    Tafluprost ethyl amide is a prostaglandin derivative. Tafluprost ethyl amide is capable of intraocular pressure (IOP) reduction and influencing eyelash growth. Tafluprost ethyl amide can be used in antiglaucoma ophthalmic compositions or cosmetics .
    Tafluprost ethyl amide
  • HY-B0601
    Tafluprost acid
    1 Publications Verification

    AFP-172

    		 Prostaglandin Receptor Drug Metabolite Cardiovascular Disease Neurological Disease Endocrinology
    Tafluprost acid (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor (IC50=67 nM) than for the prostanoid FP receptor. Tafluprost acid can be used in the research of glaucoma .
    Tafluprost acid
  • HY-B0600R
    Tafluprost (Standard)

    		Others Cardiovascular Disease Others
    Tafluprost (Standard) is the analytical standard of Tafluprost. This product is intended for research and analytical applications. Tafluprost (AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Tafluprost can inhibit the apoptosis of retinal ganglion cells (RGCs) and rat RGCs cells. Tafluprost promotes axon regeneration by regulating Zn2+-mTORpathway, inhibits intracellular lipid accumulation in human preorbital adipocytes. Tafluprost can be used in the study of optic nerve injury in glaucoma [4] .
    Tafluprost (Standard)
  • HY-139420R
    Tafluprost ethyl amide (Standard)

    		Others Others
    Tafluprost ethyl amide (Standard) is the analytical standard of Tafluprost ethyl amide. This product is intended for research and analytical applications. Tafluprost ethyl amide is a prostaglandin derivative. Tafluprost ethyl amide is capable of intraocular pressure (IOP) reduction and influencing eyelash growth. Tafluprost ethyl amide can be used in antiglaucoma ophthalmic compositions or cosmetics .
    Tafluprost ethyl amide (Standard)
  • HY-116733
    Tafluprost ethyl ester

    AFP-175

    		 Prostaglandin Receptor Others
    Tafluprost ethyl ester (AFP-175) is a derivative of Prostaglandin F2α (PGF2α) (HY-12956). Tafluprost ethyl ester is an agonist for prostaglandin FP receptor, and exhibits miotic effect .
    Tafluprost ethyl ester
  • HY-118294
    15-OH Tafluprost

    16-Phenoxy tetranor prostaglandin F2α isopropyl ester; 16-Phenoxy tetranor PGF2α isopropyl ester

    		 Others Cardiovascular Disease
    15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments .
    15-OH Tafluprost

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