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Wnt3a

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Porcupine (1) Small Interfering RNA (siRNA) (1) Wnt (4) β-catenin (1)
By Research Areas:	Cancer (4)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-122832

ABC99	Wnt	Cancer
ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC₅₀=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM .

HY-153855

Zamaporvint RXC004	Wnt Acyltransferase Porcupine	Cancer
Zamaporvint (RXC004) is an orally active and selective inhibitor of *Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine* and inhibited *Wnt* ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in *Wnt* ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research .

HY-RS15835

WNT3A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
WNT3A Human Pre-designed siRNA Set A contains three designed siRNAs for WNT3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

WNT3A Human Pre-designed siRNA Set A WNT3A Human Pre-designed siRNA Set A

HY-P10204

FZD7 antagonist 1	Wnt	Cancer
FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the *wnt3a* with IC₅₀ value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .

HY-160709

Wnt/β-catenin-IN-2	Wnt β-catenin	Cancer
Wnt/β-catenin-IN-2 (Compound 3235-0367) is a *Wnt/β-catenin* signaling pathway inhibitor, with IC₅₀ and K_D values of 7.1 and 2.5 μM, respectively. Wnt/β-catenin-IN-2 can be used for the research of cancer .

Cat. No.	Product Name	Target	Research Area

HY-P10204

FZD7 antagonist 1	Wnt	Cancer
FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the *wnt3a* with IC₅₀ value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .

Species:	Human (4) Mouse (1)
Tag:	His (2) Fc (3)
Source:	HEK293 (3) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P70452

	Wnt3a Protein, Mouse (His) Wnt-3a; Wnt 3a; Wnt3a protein; Wnt3a	Mouse	E. coli
	Wnt-3a protein is a Frizzled receptor ligand that activates TCF/LEF transcription factors in the canonical Wnt pathway, which is critical for embryonic mesoderm development, somite formation, neural tube morphogenesis, and stem cell self-renewal in vitro. Formation of a 1:1 complex with AFM ensures prolonged biological activity and may represent its physiological form. Wnt3a Protein, Mouse (His) is the recombinant mouse-derived Wnt3a, expressed by E. coli , with N-10*His labeled tag. ,

HY-P70453C

	Wnt3a Surrogate Protein, Human (HEK293, C-hFc) 2 Publications Verification Wnt-3a; Wnt 3a; Wnt3a protein; Wnt3a	Human	HEK293
	Wnt3a Surrogate Protein, Human (HEK293, C-hFc) is the recombinant human-derived Wnt3a Surrogate, expressed by HEK293 , with C-hFc labeled tag. ,

HY-P70453A

	Wnt3a Protein, Human (His) 5 Publications Verification MGC119418; MGC119419; MGC119420; protein Wnt-3a; wingless-type MMTV integration site family, member 3a; Wnt3a; Wnt-3a	Human	E. coli
	Wnt3a protein is a ligand of Frizzled receptors and can activate TCF/LEF transcription factors in the canonical Wnt pathway. It is essential for embryonic mesoderm development, caudal somite formation, neural tube morphogenesis, and intestinal crypt stem cell self-renewal. Wnt3a Protein, Human (His) is the recombinant human-derived Wnt3a protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70453B

	Wnt3a Surrogate Protein, Human (HEK293, Fc) 2 Publications Verification Wnt3a Surrogate, Human (HEK293, Fc)	Human	HEK293
	Wnt3a Surrogate protein is a Wnt recombination protein that plays an important role in embryonic development, adult tissue homeostasis and injury repair. Wnt3a Surrogate protein, consisting of the domain and Fc portion of Wnt3a, helps organoids expand and maintain a source of Wnt. Organoids are a rapidly evolving model system for tissue development, and Wnt3a is considered as the essential protein for organoid growth. Wnt3a or the small molecule glycogen synthase kinase 3 (GSK3) inhibitor CHIR are commonly used as Wnt sources in experiments. However, the application of Wnt3a is hampered by Wnt lipidation, and cross-reactivity with Wnt frizzled (Fzd). Therefore, Wnt3a Surrogate protein was used instead of Wnt3a, as a water-soluble and Fzd-specific alternative Wnt agonist. And the Wnt3a Surrogate protein exhibits tissue selectivity consistent with Fzd isoform specificity. Wnt3a Surrogate Protein, Human (HEK293, Fc) is a recombinant Wnt3a protein of human origin. It is expressed by HEK293 cells with an Fc tag.

HY-P70453D

	Wnt3a Surrogate Protein, Human (HEK293, N-hFc) Wnt3a Surrogate, Human (HEK293, N-hFc)	Human	HEK293

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HY-P83724

	Wnt3a Antibody MGC119418; MGC119419; MGC119420; Protein Wnt 3a Precursor; Protein Wnt-3a; Wingless type MMTV integration site family member 3a; Wnt 3a; Wnt3a protein.	WB, IHC-P, ICC/IF	Human
	Wnt3a Antibody is a non-conjugated and Rabbit origined Polyclonal antibody about 39 kDa, targeting to Wnt3a . It can be used for WB, IHC-P, IF assays with tag free, in the background of Human.

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WNT3A Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
WNT3A Human Pre-designed siRNA Set A contains three designed siRNAs for WNT3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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