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Results for "

dystrophin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CDK (1) Nucleoside Antimetabolite/Analog (2)
By Research Areas:	Metabolic Disease (3)
Oligonucleotides:	Antisense Oligonucleotides (11)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101459

RTC13	Others	Metabolic Disease
RTC13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy (DMD) .

HY-132586A

Viltolarsen sodium NS-065/NCNP-01 sodium	Nucleoside Antimetabolite/Analog	Metabolic Disease
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .

HY-123359

RTC14	Others	Others
RTC14 is a read-through compound (RTC) that can induce ribosomes to bypass nonsense mutations in mRNA and allow the production of full-length functional proteins. RTC14 has the potential to be used in the research of various genetic disorders, such as nonsense mutations in the ataxia-telangiectasia mutated (ATM) gene and the dystrophin gene .

HY-132586

Viltolarsen NS-065/NCNP-01	Nucleoside Antimetabolite/Analog	Metabolic Disease
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .

HY-122631

TG693	CDK	Others
TG693 is an orally active inhibitor of CLK1. TG693 regulates the mutated exon 31 of the dystrophin gene in vivo. TG693 is used in Duchenne muscular dystrophy (DMD) research .

HY-163665

AHR antagonist 8	Others	Others
AHR antagonist 8 (compound SG-02) is a regulator of utrophin, a homolog of dystrophin, and an AhR antagonist (Kd: 41.68 nM). Studies have shown that 800 nM of AHR antagonist 8 can upregulate utrophin by 2.7 times. AHR antagonist 8 also stimulates increased MyHC expression, suggesting that it has the potential to enhance myogenesis. After ADME evaluation, AHR antagonist 8 also has a certain oral bioavailability .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83479

	Dystrophin Antibody (YA3224) BMD; CMD3B; DMD; dystrophin	WB	Human, Mouse, Rat
	Dystrophin Antibody (YA3224) is a biotin-conjugated non-conjugated IgG antibody, targeting Dystrophin, with a predicted molecular weight of 427 kDa (observed band size: 427 kDa). Dystrophin Antibody (YA3224) can be used for WB experiment in human, mouse, rat background.

HY-P83716

	Alpha-dystroglycan Antibody 156DAG antibody; A3a antibody; AGRNR antibody; Alpha dystroglycan antibody; Alpha-DG antibody; Beta-DG antibody; Beta-dystroglycan antibody; DAG antibody; Dag1 antibody; DAG1_HUMAN antibody; Dystroglycan 1 (dystrophin associated glycoprotein 1) antibody; Dystroglycan antibody; dystrophin associated glycoprotein 1 antibody; dystrophin-associated glycoprotein 1 antibody; OTTHUMP00000210857 antibody; OTTHUMP00000210858 antibody	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Alpha-dystroglycan Antibody is an unconjugated, approximately 97 kDa, rabbit-derived, anti-Alpha-dystroglycan polyclonal antibody. Alpha-dystroglycan Antibody can be used for: WB, IHC-P, IF-Cell, FC expriments in human,mouse and rat background without labeling.

HY-P82323

	alpha Sarcoglycan Antibody (YA2068) SGCA; ADL; DAG2; Alpha-sarcoglycan; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2	WB, IHC-P, IP	Human, Mouse, Rat
	alpha Sarcoglycan Antibody (YA2068) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2068), targeting alpha Sarcoglycan, with a predicted molecular weight of 43 kDa (observed band size: 50 kDa). alpha Sarcoglycan Antibody (YA2068) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-132586A

Viltolarsen sodium NS-065/NCNP-01 sodium		Antisense Oligonucleotides
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132584A

Casimersen sodium SRP-4045 sodium		Antisense Oligonucleotides
Casimersen sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-145724A

Drisapersen sodium Kyndrisa sodium; GSK2402968A sodium; PRO051 sodium		Antisense Oligonucleotides
Drisapersen sodium, a antisense oligonucleotide, induces exon 51 skipping during *dystrophin* pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-150237

FITC-labeled Drisapersen sodium		Antisense Oligonucleotides
FITC-labeled Drisapersen (sodium) is Drisapersen labeled with FITC. Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-132611A

Golodirsen sodium SRP-4053 sodium		Antisense Oligonucleotides
Golodirsen sodium is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets *exon 53 of dystrophin* pre-mRNA**. Golodirsen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-147253

Brogidirsen NS 089; NCNP 02		Antisense Oligonucleotides
Brogidirsen exerts the stimulatory function of synthesis of functional *dystrophin* .

HY-147253A

Brogidirsen sodium NS 089 sodium; NCNP 02 sodium		Antisense Oligonucleotides
Brogidirsen sodium exerts the stimulatory function of synthesis of functional *dystrophin* .

HY-132584

Casimersen SRP-4045		Antisense Oligonucleotides
Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-145724

Drisapersen Kyndrisa; GSK2402968A; PRO051		Antisense Oligonucleotides
Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during *dystrophin* pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-132586

Viltolarsen NS-065/NCNP-01		Antisense Oligonucleotides
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132611

Golodirsen SRP-4053		Antisense Oligonucleotides
Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets *exon 53 of dystrophin* pre-mRNA**. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD) .

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