2. Oligonucleotides
  3. Antisense Oligonucleotides
  4. Golodirsen sodium

Golodirsen sodium  (Synonyms: SRP-4053 sodium)

Cat. No.: HY-132611A Purity: 92.00%
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Golodirsen sodium is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen sodium can be used for the research of Duchenne muscular dystrophy (DMD).

For research use only. We do not sell to patients.

RNA, [P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(G-m5U-m5U-G-C-C-m5U-C-C-G-G-m5U-m5U-C-m5U-G-A-A-GG-m5U-G-m5U-m5U-C), 5'-[P-[4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]carbonyl]-1-piperazinyl]-N,Ndimethylphosphonamidate], sodium salt

Golodirsen sodium Chemical Structure

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1 mg USD 259 In-stock
5 mg USD 648 In-stock
10 mg USD 1057 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Golodirsen sodium Related Antibodies

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Description

Golodirsen sodium is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen sodium can be used for the research of Duchenne muscular dystrophy (DMD)[1][2].

Molecular Weight

9222.01

Formula

C305H481N138Na25O112P25
Appearance

Solid

Color

White to off-white

SMILES

[Golodirsen (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Purity & Documentation

Purity: 92.00%

COA (245 KB) RP-HPLC (96 KB)

Handling Instructions (2659 KB)
References
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Golodirsen sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GolodirsenSRP-4053SRP4053SRP 4053OthersPMOexon53mRNADuchennemusculardystrophyDMDInhibitorinhibitorinhibit

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