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Results for "

endogenous ceramide

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126015
    P053

    		Acyltransferase Metabolic Disease
    P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor wirh an IC50 of 0.5 μM. P053 acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle. Whole-body adiposity regulator .
    P053
  • HY-154831
    C22-Ceramide

    N-Behenoyl-D-erythro-sphingosine; Cer d18:1/22:0

    		 Liposome Metabolic Disease
    C22-Ceramide (Cer d18:1/22:0) is an endogenous bioactive sphingolipid. C22-Ceramide reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes .
    C22-Ceramide
  • HY-113679
    Ceramides Mixture
    1 Publications Verification

    		 Telomerase Metabolic Disease Endocrinology
    Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity .
    Ceramides Mixture
  • HY-N10634
    D-Glucosyl-β-1,1′-N-palmitoylsphingosine

    C16 Glucosyl(β) ceramide (d18:1/16:0)

    		 Others Inflammation/Immunology
    D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) is an endogenous Mincle ligand possessing immunostimulatory activity .
    D-Glucosyl-β-1,1′-N-palmitoylsphingosine
  • HY-124962
    D-NMAPPD
    1 Publications Verification

    (1R,2R)-B13

    		 iGluR Neurological Disease Cancer
    D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor. D-NMAPPD regulates NMDA receptor properties by enhancing endogenous production of ceramides. D-NMAPPD has anticancer effecs .
    D-NMAPPD
  • HY-D1574
    C6 NBD Sphingomyelin

    		Fluorescent Dye Others
    C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .
    C6 NBD Sphingomyelin
  • HY-124177A
    C14 Ceramide (d18:1/14:0)

    		Endogenous Metabolite Neurological Disease Metabolic Disease
    C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research .
    C14 Ceramide (d18:1/14:0)
  • HY-124134
    AD-2646

    LCL102

    		 Ceramidase Caspase PARP Cancer
    AD-2646 (LCL102), a ceramide analog, can kill leukemic T cells (EC50: 40 μM). AD-2646 triggers the cleavage of caspase-8, -9 and -3, as well as the caspase substrate PARP. AD-2646 is a ceramidase inhibitor. AD-2646 induces an accumulation of endogenous ceramide owing to perturbed ceramide metabolism .
    AD-2646

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