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Results for "

peripheral arterial disease

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adenosine Receptor (1) Calcium Channel (1) Dopamine Receptor (1) Protease Activated Receptor (PAR) (1) Thrombin (1)
By Research Areas:	Cardiovascular Disease (5) Inflammation/Immunology (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0484

Buflomedil hydrochloride	Others	Others
Buflomedil hydrochloride is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.

HY-122365R

Inositol nicotinate (Standard)	Others	Cardiovascular Disease
Inositol nicotinate (Standard) is the analytical standard of Inositol nicotinate. This product is intended for research and analytical applications. Inositol nicotinate, with vasodilatory effect, is used in the study of Peripheral arterial disease (PAD) .

HY-122365

Inositol nicotinate Inositol niacinate; Hexanicit	Others	Cardiovascular Disease
Inositol nicotinate (Hexanicit) has vasodilating effects and can be used in research on peripheral arterial disease, showing efficacy when taken orally. Inositol nicotinate does not significantly improve triglyceride levels in mice induced by biphenyl esters .

HY-100897

Sulodexide	Thrombin	Cardiovascular Disease
Sulodexide is an orally active mixture of glycosaminoglycans composed of low molecular weight heparin (80%) and dermatan sulfate (20%). Sulodexide exhibits antithrombotic activity through interaction with antithrombin III (AT III) and heparin cofactor II (HC II), and inhibition of thrombin formation. Sulodexide exhibits profibrinolytic activity through release of tissue plasminogen activator (tPA). Sulodexide exhibits endothelial protective and anti-inflammatory effect, ameliorates chronic venous disease .

HY-143313

Protease-Activated Receptor-1 antagonist 1	Protease Activated Receptor (PAR)	Cardiovascular Disease
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor-1 (PAR-1) antagonist with the IC₅₀ of 3 nM by FLIPR technology. Protease-Activated Receptor-1 antagonist 1 can be used for the research of thrombotic cardiovascular, myocardial infarction, and peripheral arterial disease .

HY-106904

Nexopamil	Calcium Channel 5-HT Receptor Dopamine Receptor	Cardiovascular Disease
Nexopamil is a calcium antagonist of Ca ²⁺ channel, 5HT₂, 5HT_1A, 5HT_1C and dopamine D₂ receptors. Nexopamil exhibits vasodilatory, cardioprotective, and platelet aggregation inhibiting effects. Nexopamil can be used for researches of stable or unstable angina and possibly of peripheral arterial occlusive disease .

HY-161718

MRS8028	Adenosine Receptor	Inflammation/Immunology
MRS8028 is an agonist for A3 adenosine receptor (A3AR), which binds hA3AR with K_i of 2.44 nM. MRS8028 is potential for ameliorating ischemia and inflammatory diseases .

Cat. No.	Product Name

HY-L046

Anti-Cardiovascular Disease Compound Library	1,657 compounds
Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels which include coronary heart disease, cerebrovascular disease, peripheral arterial disease, rheumatic heart disease, etc. CVDs are the number 1 cause of death globally. Smoking, unhealthy nutrition, aging population, lack of physical activity, arterial hypertension, or diabetes can promote cardiovascular disease like myocardial infarction or stroke. It is multifactorial and encompasses a multitude of mechanisms, such as eNOS uncoupling, reactive oxygen species formation, chronic inflammatory disorders and abnormal calcium homeostasis. Antioxidant, anti-inflammatory and anti-diabetes agents may reduce the cardiovascular disease risk. MCE supplies a unique collection of 1,657 compounds with confirmed anti-cardiovascular activity. These compounds mainly target metabolic enzyme, membrane transporter, ion channel, inflammation related signaling pathways. MCE Anti-Cardiovascular Disease Compound Library can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

Anti-Cardiovascular Disease Compound Library

1,657 compounds

Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels which include coronary heart disease, cerebrovascular disease, peripheral arterial disease, rheumatic heart disease, etc. CVDs are the number 1 cause of death globally. Smoking, unhealthy nutrition, aging population, lack of physical activity, arterial hypertension, or diabetes can promote cardiovascular disease like myocardial infarction or stroke. It is multifactorial and encompasses a multitude of mechanisms, such as eNOS uncoupling, reactive oxygen species formation, chronic inflammatory disorders and abnormal calcium homeostasis. Antioxidant, anti-inflammatory and anti-diabetes agents may reduce the cardiovascular disease risk.

MCE supplies a unique collection of 1,657 compounds with confirmed anti-cardiovascular activity. These compounds mainly target metabolic enzyme, membrane transporter, ion channel, inflammation related signaling pathways. MCE Anti-Cardiovascular Disease Compound Library can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-122365

Inositol nicotinate Inositol niacinate; Hexanicit	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Others
Inositol nicotinate (Hexanicit) has vasodilating effects and can be used in research on peripheral arterial disease, showing efficacy when taken orally. Inositol nicotinate does not significantly improve triglyceride levels in mice induced by biphenyl esters .

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