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Results for "

pluripotency

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aryl Hydrocarbon Receptor (1) Biochemical Assay Reagents (1) DYRK (1) HSP (1)
By Research Areas:	Cancer (1)

Inhibitors & Agonists

Screening Libraries

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15838

ID-8 4 Publications Verification	DYRK	Cancer
ID-8 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase (DYRK). ID-8 sustains embryonic stem cell (ESC) self-renewal and pluripotency. ID-8 enhances Wnt-mediated hESC survival and proliferation via inhibition of DYRKs .

HY-P10706

Ac-ILVAGK-NH2	Biochemical Assay Reagents	Others
Ac-ILVAGK-NH2 is a self-assembling peptide that helps human H1 embryonic stem cells maintain their pluripotency .

HY-111002

Displurigen NSC375009	HSP	Others
Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC₅₀ = 225 μM) .

HY-15001A

Stemregenin 1 hydrochloride SR1 hydrochloride	Aryl Hydrocarbon Receptor	Others
Stemregenin 1 hydrochloride is a purine derivative that antagonizes aryl hydrocarbon receptor signaling in CD34+ cells. IC₅₀ The value is 127 nM. Stemregenin 1 hydrochloride can be used to expand the pluripotency of hematopoietic stem cells (HSC) in stem cell studies .

Cat. No.	Product Name

HY-L017

Stem Cell Signaling Compound Library	2,005 compounds
Adult stem cells are important for tissue homeostasis and regeneration due to their ability to self-renew and generate multiple types of differentiated daughters. Self-renewal is reflected by their capacity to undergo multiple/limitless divisions. Several signaling pathways are involved in self-renewal of stem cells, that is, Notch, Wnt, and Hedgehog pathways or Polycomb family proteins. Recent studies mainly focus on cancer stem cell (CSCs), induced pluripotent stem cell (iPSCs), neural stem cell and maintenance of embryonic stem cell pluripotency. Among them, CSCs have been believed to be responsible for tumor initiation, growth, and recurrence that have implications for cancer therapy. MCE owns a unique collection of 2,005 compounds that can be used for stem cell regulatory and signaling pathway research.

Stem Cell Signaling Compound Library

2,005 compounds

Adult stem cells are important for tissue homeostasis and regeneration due to their ability to self-renew and generate multiple types of differentiated daughters. Self-renewal is reflected by their capacity to undergo multiple/limitless divisions. Several signaling pathways are involved in self-renewal of stem cells, that is, Notch, Wnt, and Hedgehog pathways or Polycomb family proteins. Recent studies mainly focus on cancer stem cell (CSCs), induced pluripotent stem cell (iPSCs), neural stem cell and maintenance of embryonic stem cell pluripotency. Among them, CSCs have been believed to be responsible for tumor initiation, growth, and recurrence that have implications for cancer therapy.

MCE owns a unique collection of 2,005 compounds that can be used for stem cell regulatory and signaling pathway research.

Ac-ILVAGK-NH2	Biochemical Assay Reagents	Others
Ac-ILVAGK-NH2 is a self-assembling peptide that helps human H1 embryonic stem cells maintain their pluripotency .

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