Search Result

Results for "

sensation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Dehydrogenase (ALDH) (2) Autophagy (1) Bacterial (2) Bradykinin Receptor (3) Calcium Channel (1) Dopamine Receptor (1) Drug Metabolite (1) FAAH (1) Fungal (2) Isotope-Labeled Compounds (1) Sodium Channel (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (4) Infection (2) Inflammation/Immunology (5) Neurological Disease (8)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1243

Propoxycaine hydrochloride 1 Publications Verification	Sodium Channel	Neurological Disease
Propoxycaine hydrochloride inhibits voltage-gated sodium channels, and thereby inhibits the ionic flux required for the initiation and conduction of impulses. Propoxycaine hydrochloride application can lead to a loss of sensation.

HY-14380

PF-3845 1 Publications Verification	FAAH Autophagy	Inflammation/Immunology Cancer
PF-3845 is a potent, selective, irreversible and orally active inhibitor of fatty acid amide hydrolase (FAAH), with a K_i of 0.23 μM. PF-3845 is a covalent inhibitor that carbamylates FAAH's serine nucleophile. PF-3845 can reduce pain sensation, inflammation, and anxiety/depression without substantial effects on motility or cognition .

HY-121870

Dimethocaine Larocaine	Dopamine Receptor	Neurological Disease
Dimethocaine (Larocaine) can alleviate pain and sensation by blocking the sodium ion channels inside neurons .

HY-W014394

Vanillyl butyl ether	Others	Cardiovascular Disease
Vanillyl butyl ether is a major contributor to the characteristic flavor and fragrance of vanilla. Vanillyl butyl ether is one of the eco-friendly and nontoxic substances. Vanillyl butyl ether has been proposed as a mild warming agent providing a warming sensation and enhancing the blood circulation .

HY-B0364A

Dyclonine hydrochloride 1 Publications Verification Dyclocaine hydrochloride	Bacterial Fungal Aldehyde Dehydrogenase (ALDH)	Infection Cancer
Dyclonine (Dyclocaine) hydrochloride is an orally effective ALDH covalent inhibitor (crosses blood-brain barrier), with an IC₅₀ of 35 μM for ALDH2 and 76 μM for ALDH3A1. Dyclonine hydrochloride has sensitizing activities for targeted cancer cells and antibacterial. Dyclonine hydrochloride is also a local agent that can suppress or relieve pain. that blocks the transmission of various nerve impulses or stimuli and inhibits the sensation of touch and pain .

HY-N7014

Hydroxyl-γ-isosanshool	Others	Neurological Disease
Hydroxyl-γ-isosanshool is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. Hydroxyl-γ-isosanshoo induces a numbing sensation .

HY-106325

AA 2379	Others	Inflammation/Immunology
AA 2379 is an orally active antirheumatic agent. AA 2379 has antiinflammatory, antipyretic activities and reduces pain sensation .

HY-N7013

Hydroxy-Epsilon-Sanshool	Others	Neurological Disease
Hydroxy-Epsilon-Sanshool is an alkylamide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensates, and its content is important in determinant the pungency intensity of Zanthoxylum bungeanum .

HY-103293

Lys-Bradykinin Kallidin (380-389) (human, porcine, bovine)	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin, a kind of kallidin and bradykinin receptor ligand, can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin, also a vasodilator, can widen blood vessels and increase blood flow. ys-Bradykinin stimulates net Na+ influx, and also the DNA synthesis. Lys-Bradykinin involves in vascular regulation, inflammation and pain sensation .

HY-N1369R

Menthol (Standard)	Calcium Channel	Neurological Disease Cancer
Menthol (Standard) is the analytical standard of Menthol. This product is intended for research and analytical applications. Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .

HY-103293B

Lys-Bradykinin tetraacetate Kallidin (380-389) (human, porcine, bovine) tetraacetate	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin (Kallidin (380-389) (human, porcine, bovine)) tetraacetate, a kind of kallidin and bradykinin receptor ligand, can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin tetraacetate, also a vasodilator, can widen blood vessels and increase blood flow. ys-Bradykinin stimulates net Na+ influx, and also the DNA synthesis. Lys-Bradykinin tetraacetate involves in vascular regulation, inflammation and pain sensation .

HY-103293A

Lys-Bradykinin TFA Kallidin (380-389) (human, porcine, bovine) TFA	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin TFA is the TFA salt form of Lys-Bradykinin (HY-103293). Lys-Bradykinin TFA is a ligand for kallidin and bradykinin receptor, which can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin TFA serves as a vasodilator, which widens blood vessels and increases blood flow. Lys-Bradykinin TFA stimulates net Na+ influx, and contributes to DNA synthesis. Lys-Bradykinin TFA involves in vascular regulation, inflammation and pain sensation .

HY-N9484S

Menthofuran-13C2	Drug Metabolite Isotope-Labeled Compounds	Others
Menthofuran- ¹³C₂ is ¹³C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca ⁺⁺ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .

HY-B0364AR

Dyclonine hydrochloride (Standard)	Bacterial Fungal Aldehyde Dehydrogenase (ALDH)	Infection Cancer
Dyclonine (hydrochloride) (Standard) is the analytical standard of Dyclonine (hydrochloride). This product is intended for research and analytical applications. Dyclonine (Dyclocaine) hydrochloride is an orally effective ALDH covalent inhibitor (crosses blood-brain barrier), with an IC_{50_{of 35 μM for ALDH2 and 76 μM for ALDH3A1. Dyclonine hydrochloride has sensitizing activities for targeted cancer cells and antibacterial. Dyclonine hydrochloride is also a local agent that can suppress or relieve pain. that blocks the transmission of various nerve impulses or stimuli and inhibits the sensation of touch and pain .}}

Cat. No.	Product Name	Target	Research Area

HY-103293A

Lys-Bradykinin TFA Kallidin (380-389) (human, porcine, bovine) TFA	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin TFA is the TFA salt form of Lys-Bradykinin (HY-103293). Lys-Bradykinin TFA is a ligand for kallidin and bradykinin receptor, which can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin TFA serves as a vasodilator, which widens blood vessels and increases blood flow. Lys-Bradykinin TFA stimulates net Na+ influx, and contributes to DNA synthesis. Lys-Bradykinin TFA involves in vascular regulation, inflammation and pain sensation .

HY-103293

Lys-Bradykinin Kallidin (380-389) (human, porcine, bovine)	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin, a kind of kallidin and bradykinin receptor ligand, can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin, also a vasodilator, can widen blood vessels and increase blood flow. ys-Bradykinin stimulates net Na+ influx, and also the DNA synthesis. Lys-Bradykinin involves in vascular regulation, inflammation and pain sensation .

HY-103293B

Lys-Bradykinin tetraacetate Kallidin (380-389) (human, porcine, bovine) tetraacetate	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin (Kallidin (380-389) (human, porcine, bovine)) tetraacetate, a kind of kallidin and bradykinin receptor ligand, can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin tetraacetate, also a vasodilator, can widen blood vessels and increase blood flow. ys-Bradykinin stimulates net Na+ influx, and also the DNA synthesis. Lys-Bradykinin tetraacetate involves in vascular regulation, inflammation and pain sensation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W014394

Vanillyl butyl ether	Cardiovascular Disease Structural Classification Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	Others
Vanillyl butyl ether is a major contributor to the characteristic flavor and fragrance of vanilla. Vanillyl butyl ether is one of the eco-friendly and nontoxic substances. Vanillyl butyl ether has been proposed as a mild warming agent providing a warming sensation and enhancing the blood circulation .

HY-N7014

Hydroxyl-γ-isosanshool	Natural Products Source classification Myrtaceae Plants Syzygium aromaticum	Others
Hydroxyl-γ-isosanshool is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. Hydroxyl-γ-isosanshoo induces a numbing sensation .

HY-N7013

Hydroxy-Epsilon-Sanshool	Zanthoxylum bungeanum Maxim. Natural Products Source classification Rutaceae Plants	Others
Hydroxy-Epsilon-Sanshool is an alkylamide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensates, and its content is important in determinant the pungency intensity of Zanthoxylum bungeanum .

HY-N1369R

Menthol (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Labiatae Source classification Erythrina poeppigiana Plants Endogenous metabolite	Calcium Channel
Menthol (Standard) is the analytical standard of Menthol. This product is intended for research and analytical applications. Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .

Cat. No.	Product Name	Chemical Structure

HY-N9484S

Menthofuran-13C2
Menthofuran- ¹³C₂ is ¹³C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca ⁺⁺ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .

Menthofuran-13C2

Menthofuran- ¹³C₂ is ¹³C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca ⁺⁺ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.

sensation

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products