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Results for "

thiophene,

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Antibiotic (2) Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (4) Complement System (1) Endogenous Metabolite (1) Influenza Virus (1) Isotope-Labeled Compounds (1) Parasite (1) Potassium Channel (1) Virus Protease (3) γ-secretase (1)
By Research Areas:	Cancer (5) Infection (6) Inflammation/Immunology (3) Metabolic Disease (2) Neurological Disease (6)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W012941

2-Thiophenecarboxaldehyde Thiophene-2-carboxaldehyde	Endogenous Metabolite	Metabolic Disease
2-Thiophenecarboxaldehyde is an endogenous metabolite.

HY-117145

Thiophene-2	Bacterial	Infection
Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against *Mycobacterium tuberculosis* with a MIC value of 1 μM, and has potent anti-tuberculosis activity .

HY-W004615R

Thiophene-3-carboxylic acid (Standard)	Biochemical Assay Reagents	Others
Thiophene-3-carboxylic acid (Standard) is the analytical standard of Thiophene-3-carboxylic acid. This product is intended for research and analytical applications. Thiophene-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-N3795

Thiophene E Echinoynethiophene A; Thiophene A dio	Others	Others
Thiophene E (Echinoynethiophene A) is a natural product .

HY-W004615

Thiophene-3-carboxylic acid	Biochemical Assay Reagents	Others
Thiophene-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W002251

*Benzo[b]thiophene-3-carbaldehyde*	Biochemical Assay Reagents	Others
Benzo[b]thiophene-3-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-132475S

rac-Duloxetine-d3 oxalate	Isotope-Labeled Compounds	Neurological Disease
rac Duloxetine 3-Thiophene Isomer-d3 Oxalate is a stable isotope of Duloxetine.

HY-151581

HCVcc-IN-1	Virus Protease	Infection
HCVcc-IN-1 is a benzothiazole-2-thiophene S-glycoside derivative with low toxic and antiviral activity .

HY-151588

Anticancer agent 90	Virus Protease	Cancer
Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498) .

HY-151592

Anticancer agent 91	Antibiotic	Cancer
Anticancer agent 91 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor and antiviral activity. Anticancer agent 91 has high inhibition against the two cell line from CNS cancer (SF-539 and SNB-75) .

HY-151587

Anticancer agent 89	Others	Cancer
Anticancer agent 89 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity, has high inhibition against the three cell line from ovarian cancer (OVCAR-4), renal cancer (A498), and melanoma (SK-MEL-5) .

HY-B0973

Dibenzothiophene DBT; Diphenylene sulfide	Others	Others
Dibenzothiophene is an organic synthesis intermediate consisting of two benzene rings fused to a central thiophene ring.

HY-151589

HCVcc-IN-2	Virus Protease	Infection Cancer
HCVcc-IN-2 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor and antiviral activity. HCVcc-IN-2 has high inhibition against the three cell line from CNS cancer (SF-539 and SNB-75), colon cancer (HCT-116), and renal cancer (A498) .

HY-12384

Tenosal	Others	Inflammation/Immunology
Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties.

HY-148548

p-HTAA	Amyloid-β	Neurological Disease
p-HTAA is a pentamer hydrogen thiophene acetic acid. p-HTAA specifically labels Aβ deposits in the mice living brain .

HY-W159102

8CN	Parasite	Infection
8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis .

HY-163521

Neuraminidase-IN-19	Influenza Virus	Cancer
Neuraminidase-IN-19 (compound 5n) is an inhibitor (IC₅₀: 0.13 μM) of neuraminidase with a thiophene ring (neuraminidase) and has anticancer activity .

HY-B0973R

Dibenzothiophene (Standard)	Others	Others
Dibenzothiophene (Standard) is the analytical standard of Dibenzothiophene. This product is intended for research and analytical applications. Dibenzothiophene is an organic synthesis intermediate consisting of two benzene rings fused to a central thiophene ring.

HY-117817

Ranelic acid	Others	Metabolic Disease
Ranelic acid is an organic acid with metal cation chelating activity. Ranelic acid can be used to inhibit osteoporosis and increase bone mineral density. Ranelic acid derivatives exhibit highly substituted thiophene ring structures .

HY-13769A

TPT-260 Dihydrochloride NSC55712; TPU-260 Dihydrochloride	Others	Others
TPT-260 Dihydrochloride (NSC55712) is a thiophene thiourea derivative with molecule weight 260.00 in free base form; There is no formal name yet, we temporally call this molecule as TPT-260.

HY-14175

Begacestat GSI-953	γ-secretase	Neurological Disease
Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC₅₀Aβ₄₀=15 nM) for the treatment of Alzheimer's disease .

HY-N2048

2,2':5',2''-Terthiophene α-Terthiophene; α-Terthienyl; Trithiophene	Bacterial Antibiotic	Infection
2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.

HY-13769

TPT-260 TPU260	Others	Neurological Disease
TPT-260(TPU260) is a thiophene thiourea derivative with molecule weight 260.00 in free base form; There is no formal name yet, we temporally call this molecule as TPT-260.

HY-148431

Antimicrobial agent-14	Bacterial	Infection
Antimicrobial agent-14, a benzyl thiophene sulfonamide derivative is an antimicrobial agent, with a MIC of 200 μM against Campylobacter coli ATCC33559. Antimicrobial agent-14 can be used for the research of bacterial foodborne gastroenteritis .

HY-59299

3-Bromothiophene 3-Bromothiophene	Biochemical Assay Reagents	Others
3-Bromothiophene is a bromine atom-substituted 3-halogenated thiophene with electrochemical stability, small porosity, and high π-π* lowest transition energy. 3-Bromothiophene is often used as a conductive polymer monomer .

HY-138161

JR14a 2 Publications Verification	Complement System	Inflammation/Immunology
JR14a is a potent thiophene antagonist of human complement C3a receptor. JR14a shows selectivity for the human C3a receptor over C5a receptor. JR14a can suppress C3aR-mediated inflammation .

HY-104027

ML402 1 Publications Verification	Potassium Channel	Neurological Disease
ML402, a thiophene-carboxamide, is a selective K_2P2.1(TREK-1) and K_2P10.1(TREK-2) activator. ML402 is inactive against K_2P4.1(TRAAK) .

HY-120553

B-355252	Apoptosis	Neurological Disease
B355252, a phenoxy thiophene sulfonamide small molecule, is a potent NGF receptor agonist. B355252 potentiates NGF-induced neurite outgrowth. B355252 protects ischemic neurons from neuronal loss by attenuating DNA damage, reducing ROS production and the LDH level, and preventing neuronal apoptosis. B355252 has anti-apoptotic effects in glutamate-induced excitotoxicity, as well as in a murine hippocampal cell line (HT22) model of Parkinson disease (PD) .

HY-124987

MRS4458	Others	Inflammation/Immunology
MRS4458 is a P2Y14 receptor antagonist with anti-inflammatory activity. MRS4458 mediates inflammatory activity by activating the motility of neutrophils. The design of MRS4458 is based on the interaction with the P2Y14 receptor and optimized by molecular dynamic simulation. MRS4458 performs well in terms of shape and complementarity with the receptor. The prediction that the 5-phenyl group of MRS4458 is substituted with thiophene is generally consistent with empirical results. The biological activity of MRS4458 was verified by fluorescence assay, showing its potent antagonistic effect .

Cat. No.	Product Name	Type

HY-59299

3-Bromothiophene 3-Bromothiophene	Biochemical Assay Reagents
3-Bromothiophene is a bromine atom-substituted 3-halogenated thiophene with electrochemical stability, small porosity, and high π-π* lowest transition energy. 3-Bromothiophene is often used as a conductive polymer monomer .

HY-W004615R

Thiophene-3-carboxylic acid (Standard)	Biochemical Assay Reagents
Thiophene-3-carboxylic acid (Standard) is the analytical standard of Thiophene-3-carboxylic acid. This product is intended for research and analytical applications. Thiophene-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W004615

Thiophene-3-carboxylic acid	Biochemical Assay Reagents
Thiophene-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W002251

*Benzo[b]thiophene-3-carbaldehyde*	Biochemical Assay Reagents
Benzo[b]thiophene-3-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W012941

2-Thiophenecarboxaldehyde Thiophene-2-carboxaldehyde	Structural Classification Classification of Application Fields Capparis spinosa L. Ketones, Aldehydes, Acids Source classification Metabolic Disease Capparidaceae Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Thiophenecarboxaldehyde is an endogenous metabolite.

HY-N2048

2,2':5',2''-Terthiophene α-Terthiophene; α-Terthienyl; Trithiophene	Infection Structural Classification Natural Products Classification of Application Fields Source classification Erythrina melanacantha Taub. ex Harms Plants Compositae Disease Research Fields	Bacterial Antibiotic
2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.

HY-N3795

Thiophene E Echinoynethiophene A; Thiophene A dio	Structural Classification Natural Products Source classification Plants Compositae Laggera crispata (Vahl) Hepper & J. R. I. Wood	Others
Thiophene E (Echinoynethiophene A) is a natural product .

Cat. No.	Product Name	Chemical Structure

HY-132475S

rac-Duloxetine-d3 oxalate
rac Duloxetine 3-Thiophene Isomer-d3 Oxalate is a stable isotope of Duloxetine.

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thiophene,

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products