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  3. Anticancer agent 90

Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498).

For research use only. We do not sell to patients.

Anticancer agent 90 Chemical Structure

Anticancer agent 90 Chemical Structure

CAS No. : 2977251-03-7

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Description

Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498)[1].

In Vitro

Anticancer agent 90 (compound 6d) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against two cell lines, SK-MEL-5, OVCAR-4[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
Concentration: 0-200 μg/mL
Incubation Time: 24 hours
Result: Showed nontoxic under the doses of 100 μg/mL against FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cells, respectively.

Cell Viability Assay[1]

Cell Line: SK-MEL-5, OVCAR-4, and A498
Concentration: 0.01 mM
Incubation Time: 24 hours
Result: Inhibited SK-MEL-5 and OVCAR-4 cell viability by 30.64% and 30.71%, respectively.
Molecular Weight

712.81

Formula

C33H32N2O10S3

CAS No.
SMILES

[H][C@]1([C@@H]([C@H]([C@@H](O[C@@H]1COC(C)=O)SC2=C(C(N)=C(S2)C(C3=CC=C(C=C3)C)=O)C4=NC5=C(S4)C=CC=C5)OC(C)=O)OC(C)=O)OC(C)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Anticancer agent 90 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anticancer agent 90
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HY-151588
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