1. GPCR/G Protein Neuronal Signaling
  2. MCHR1 (GPR24)
  3. AMG-076 free base

AMG-076 free base is an orally bioavailable and selective MCHR1 antagonist. AMG-076 free base results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice.

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AMG-076 free base Chemical Structure

AMG-076 free base Chemical Structure

CAS No. : 693823-79-9

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Description

AMG-076 free base is an orally bioavailable and selective MCHR1 antagonist. AMG-076 free base results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice[1].

Molecular Weight

462.55

Formula

C26H33F3N2O2

CAS No.
SMILES

O=C(C1(CCN2CC[C@]3([H])CC(NC4=C5C=C(C(F)(F)F)C=C4)=C5[C@H](C)[C@@]3([H])C2)CCCCC1)O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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AMG-076 free base Related Classifications

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Product Name:
AMG-076 free base
Cat. No.:
HY-101699
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