2. Gene
  3. Smad5 - SMAD family member 5 Gene

Smad5 - SMAD family member 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Dwf-C; Madh5; MusMLP; 1110051M15Rik

Gene ID: 17129 | Gene type: protein coding

About Smad5

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in SMAD protein signal transduction; cellular response to BMP stimulus; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; osteoblast fate commitment; and transmembrane receptor protein serine/threonine kinase signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; egg cylinder; embryo mesenchyme; and genitourinary system. Orthologous to human SMAD5 (Smad Family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Smad5 Products(3)

mRNA Protein Name
NM_001164041.1 NP_001157513.1 mothers against decapentaplegic homolog 5
NM_001164042.1 NP_001157514.1 mothers against decapentaplegic homolog 5
NM_008541.3 NP_032567.1 mothers against decapentaplegic homolog 5
Protein Preferred Names Protein Names

mothers against decapentaplegic homolog 5

MAD homolog 5

Smad 5

dwarfin-C

mSmad5

mothers against DPP homolog 5

Recombinant Smad5 Proteins

Cat. No. Product Name Accession Purity
HY-P74539 SMAD5 Protein, Mouse (sf9, His-GST) P97454 (T2-S465) ≥95%
HY-P74540 SMAD5 Protein, Mouse (sf9) P97454 (T2-S465) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13396 SMAD5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smad5 NCBI NCBI:4090