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Tnf

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  • HY-P73444
    TNF-alpha/TNFSF2 Protein, Cynomolgus

    Tumor Necrosis Factor; Cachectin; Tnf-Alpha; Tnf; Tnfa; Tnfsf2; ICD1

    		 Cynomolgus E. coli
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Cynomolgus is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.
  • HY-P77543
    TNF-alpha/TNFSF2 Protein, Cynomolgus (Biotinylated)

    Tumor Necrosis Factor; Cachectin; Tnf-Alpha; Tnf; Tnfa; Tnfsf2; ICD1

    		 Cynomolgus E. coli
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Cynomolgus (Biotinylated) is a biotinylated recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.
  • HY-P73444A
    TNF-alpha/TNFSF2 Protein, Cynomolgus (N-His)

    Tumor Necrosis Factor; Cachectin; Tnf-Alpha; Tnf; Tnfa; Tnfsf2; ICD1

    		 Cynomolgus E. coli
    TNF-alpha/TNFSF2 protein binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It induces tumor cell death, fever, cachexia, cell proliferation, and cell differentiation. It also causes insulin resistance and GKAP42 protein degradation in adipocytes. Additionally, it plays a role in angiogenesis, osteoclastogenesis, and IL12 production in dendritic cells. TNF-alpha/TNFSF2 Protein, Cynomolgus (N-His) is the recombinant cynomolgus-derived TNF-alpha/TNFSF2 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P77445
    TNFRSF3/LTBR Protein, Cynomolgus (HEK293, Fc)

    Tumor Necrosis Factor Receptor Superfamily Member 3; Tnf-RIII; TnfCR; TnfR3

    		 Cynomolgus HEK293
    TNFRSF3/LTBR Protein,Cynomolgus (HEK293,  Fc) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Cynomolgus (HEK293,  Fc) is expressed by HEK293 cells and is a transmembrane protein (M225-W248) with a His tag at the C-terminus.
  • HY-P77322
    CD30L Protein, Cynomolgus (HEK293, His)

    Tnf superfamily member 8; CD153; CD30 Ligand; TnfSF8

    		 Cynomolgus HEK293
    CD30 Ligand is a B cell surface antigen and a ligand for CD30 (TNFRSF8), playing an inhibitory role in CD40-mediated immunoglobulin class switching. CD30 Ligand is also a a marker for Hodgkin lymphoma and related hematologic malignancies, involves in activation and functioning of the T cell-dependent immune system. CD30 ligand is expressed by T and B lymphocytes, macrophages, and a variety of normal haematopoietic cells and derived tumours. CD30 ligand exerts pleiotropic effects on normal and malignant lymphoid cells, including death, differentiation, or cell division. As for CD30 ligand in cynomolgus contains a transmembrane domain belonging to the tumor necrosis factor (TNF) family. CD30L Protein, Cynomolgus (HEK293, His) is 172 amino acids in length (Q63-D234) and is expressed in the HEK293 cells with a N-terminal His-tag.
  • HY-P701047
    TL1A/TNFSF15 Trimer Protein, Cynomolgus/Rhesus macaque (HEK293, His)

    TL1A; VEGI-251; TnfSF15; TL1; VEGI; VEGI192A; Tnf superfamily member 15

    		 Rhesus Macaque;Cynomolgus HEK293
    The TL1A/TNFSF15 trimeric protein is an important member of the tumor necrosis factor family and is critical for immune regulation and cellular responses. Its study enhances our understanding of immune regulation, providing potential applications for immunoassay and therapeutic development. TL1A/TNFSF15 Trimer Protein, Cynomolgus/Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque, cynomolgus-derived TL1A/TNFSF15 Trimer protein, expressed by HEK293 , with N-His labeled tag. The total length of TL1A/TNFSF15 Trimer Protein, Cynomolgus/Rhesus macaque (HEK293, His) is 180 a.a., with molecular weight of 25-35 kDa.
  • HY-P700838
    TNFRSF1A Protein, Cynomolgus (HEK293, His)

    Tnf-R1; Tnf-RI; FPF; TBP1; Tnf-R55; TnfAR; TnfR60; p55; p60; MS5; p55-R; TnfR1-d2

    		 Cynomolgus HEK293
    TNFRSF1A Protein exhibits a deficiency in conserved residue(s) crucial for feature annotation propagation. TNFRSF1A Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TNFRSF1A protein, expressed by HEK293 , with C-His labeled tag. The total length of TNFRSF1A Protein, Cynomolgus (HEK293, His) is 182 a.a., with molecular weight of 32-42 kDa.
  • HY-P76482
    TNFSF3/Lymphotoxin Beta Protein, Cynomolgus (sf9, His)

    Lymphotoxin-beta; LT-beta; Tumor necrosis factor C; Tnf-C; LTB; TnfSF3

    		 Cynomolgus Sf9 insect cells
    Lymphotoxin Beta (LT-beta) also known as TNFSF3, is a type II transmembrane glycoprotein of the TNF family. Lymphotoxin Beta binds to LTα to form membrane-anchored heterotrimers that activate canonical/noncanonical nuclear factor-κB (NF-κB) signaling thus inducing chemokine, cytokine or adhesion molecule expression, cell proliferation and cell survival. Lymphotoxin Beta also shows anti-inflammatory, anti-cancer activity. Lymphotoxin Beta regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury. TNFSF3/Lymphotoxin Beta Protein, Cynomolgus (sf9, His) is a recombinant protein with a N-Terminal His label, It consists of 197 amino acids (Q49-G244) and is produced in Sf9 insect cells.
  • HY-P77321
    CD30L Protein, Cynomolgus (HEK293, Fc)

    Tnf superfamily member 8; CD153; CD30 Ligand; TnfSF8

    		 Cynomolgus HEK293
    CD30 Ligand is a B cell surface antigen and a ligand for CD30 (TNFRSF8), playing an inhibitory role in CD40-mediated immunoglobulin class switching. CD30 Ligand is also a a marker for Hodgkin lymphoma and related hematologic malignancies, involves in activation and functioning of the T cell-dependent immune system. CD30 ligand is expressed by T and B lymphocytes, macrophages, and a variety of normal haematopoietic cells and derived tumours. CD30 ligand exerts pleiotropic effects on normal and malignant lymphoid cells, including death, differentiation, or cell division. As for CD30 ligand in cynomolgus contains a transmembrane domain belonging to the tumor necrosis factor (TNF) family. CD30L Protein, Cynomolgus (HEK293, Fc) is 172 amino acids in length (Q63-D234) and is expressed in the HEK293 cells with a N-terminal hFc-tag.

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