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Pathways Recommended: Vitamin D Related/Nuclear Receptor
Results for "

Vitamin A epoxide

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14854
    Tecarfarin

    ATI-5923

    		 Others Cardiovascular Disease
    Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin has the antithrombotic activity .
    Tecarfarin
  • HY-111186
    Flocoumafen

    WL 108366

    		 Glucocorticoid Receptor MMP Others
    Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects .
    Flocoumafen
  • HY-121400
    Hepaxanthin

    5,6-Monoepoxy Vitamin A; Vitamin A epoxide; 5,6-Epoxyretinol

    		 Endogenous Metabolite Others
    Hepaxanthin (5,6-Monoepoxy vitamin A; Vitamin A epoxide; 5,6-Epoxyretinol) is an inactive carotenoid. Hepaxanthin is metabolite of 5,6-monoepoxyvitamin A aldehyde, and accumulates in liver .
    Hepaxanthin
  • HY-113164
    Vitamin K1 2,3-epoxide

    		Endogenous Metabolite Others
    Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting .
    Vitamin K1 2,3-epoxide
  • HY-113164S
    Vitamin K1 2,3-epoxide-d7

    		Isotope-Labeled Compounds Others
    Vitamin K1 2,3-epoxide-d7 is the deuterium labeled Vitamin K1 2,3-epoxide[1].
    Vitamin K1 2,3-epoxide-d7
  • HY-14854A
    Tecarfarin sodium

    ATI-5923 sodium

    		 Others Metabolic Disease
    Tecarfarin sodium (ATI-5923 sodium) is a novel orally active non-competitive vitamin K epoxide reductase (VKOR) antagonist, impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin sodium has the antithrombotic activity .
    Tecarfarin sodium
  • HY-121814A
    (R)-Acenocoumarol

    (R)-Acenocoumarin; (R)-Nicoumalone

    		 Others Others
    (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting oral anticoagulant that, like warfarin, works by inhibiting vitamin K epoxide reductase. In vitro evaluations have shown that (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a higher intrinsic anticoagulant potency than warfarin and phenprocoumon. (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a single chiral center that produces two different enantiomeric forms. (R)-(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a longer plasma elimination half-life (6.6 hours) and a slower plasma clearance rate (1.9 L/hour) compared to the (S)-enantiomer (1.8 hours, 28.5 L/hour). (R)-(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a more potent anticoagulant in vivo than the (S)-enantiomer.
    (R)-Acenocoumarol

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