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Results for "

15-deoxy-Δ12,14-Prostaglandin D2

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Peptides

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116028
    15-deoxy-Δ12,14-Prostaglandin D2

    15-deoxy-Δ12,14-PGD2

    		 Endogenous Metabolite Cardiovascular Disease
    15-deoxy-Δ12,14-PGD2 is a metabolite of PGD2. It is an agonist of PGD2 receptor 2 (DP2) that binds DP2 (Ki=50 nM for the mouse receptor expressed in HEK293 cell membranes) and induces activation of eosinophils (EC50=8 nM). It also stimulates the recruitment of steroid receptor coactivator-1 (SRC-1) to peroxisome proliferator-activated receptor γ (PPARγ) and induces PPARγ-mediated transcription in a reporter assay when used at a concentration of 5 μM.1 15-deoxy-Δ12,14-PGD2 is cytotoxic to L1210 murine leukemia cells (IC50=0.3 μg/mL). It inhibits ADP-induced platelet aggregation (IC50=320 ng/ml) less potently than PGD2.
    <em>15-deoxy</em>-Δ12,14-<em>Prostaglandin</em> <em>D2</em>
  • HY-116028S1
    15-deoxy-Δ12,14-Prostaglandin D2-d4

    		Isotope-Labeled Compounds Others
    15-deoxy-Δ12,14-Prostaglandin D2-d4 is the deuterium labeled 15-deoxy-Δ12,14-Prostaglandin D2[1].
    <em>15-deoxy</em>-Δ12,14-<em>Prostaglandin</em> <em>D2</em>-d4
  • HY-P4406
    Abz-AGLA-Nba

    		Fluorescent Dye Others
    Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .
    Abz-<em>AGLA</em>-Nba
  • HY-P5443
    Pyrrhocoricin

    		Bacterial Others
    Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)
    Pyrrhocoricin

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