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Results for "

BMX

" in MedChemExpress (MCE) Product Catalog:

By Targets:	BMX Kinase (2) Apoptosis (1) Btk (6) EGFR (1) Reactive Oxygen Species (2) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (6) Inflammation/Immunology (3) Metabolic Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (3) siRNAs (3)

Inhibitors & Agonists

Recombinant Proteins

Oligonucleotides

Targets Recommended: BMX Kinase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-80002

BMX-IN-1 5 Publications Verification BMX kinase inhibitor	Btk BMX Kinase	Cancer
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys ⁴⁹⁶ in the BMX ATP binding domain with an IC₅₀ of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC₅₀ value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.

HY-130574

MnTE-2-PyP chloride BMX-010 chloride	Reactive Oxygen Species	Cancer
MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer .

HY-101267

*CHMFL-BMX-078* 1 Publications Verification CHMFL-BMX 078	BMX Kinase	Cancer
CHMFL-BMX-078 is a highly potent and selective type II irreversible *BMX* kinase inhibitor with an IC₅₀ of 11 nM.

HY-125662A

BMX-001	Reactive Oxygen Species Apoptosis	Metabolic Disease
BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model. BMX-001 reduces apoptosis in human and murine islets. BMX-001 significantly improves static-glucose stimulated insulin secretion (sGSIS) responses in murine islets. BMX-001 can significantly restore euglycemia in murine islet studies in the presence of the MnSOD. BMX-001 reduces the generation of ROS in a murine islet isolation and culture model .

HY-RS01557

BMX Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BMX Human Pre-designed siRNA Set A contains three designed siRNAs for BMX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BMX Human Pre-designed siRNA Set A BMX Human Pre-designed siRNA Set A

HY-RS01558

Bmx Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Bmx Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bmx gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bmx Mouse Pre-designed siRNA Set A Bmx Mouse Pre-designed siRNA Set A

HY-RS01559

Bmx Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Bmx Rat Pre-designed siRNA Set A contains three designed siRNAs for Bmx gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bmx Rat Pre-designed siRNA Set A Bmx Rat Pre-designed siRNA Set A

HY-148585

BTK-IN-22	Btk	Cancer
BTK-IN-22 is a BTK inhibitor (IC₅₀: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC₅₀s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)

HY-148594

BTK-IN-23	Btk	Cancer
BTK-IN-23 is a BTK inhibitor (IC₅₀: 12.8 nM). BTK-IN-23 also inhibits BLX and *BMX* with IC₅₀s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997) .

HY-117900A

(Rac)-PF-06250112	Btk	Inflammation/Immunology
(Rac)-PF-0625011 is a racemate of PF-06250112. PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor and shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC .

HY-117900

PF-06250112	Btk	Inflammation/Immunology
PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC₅₀ of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC₅₀s of 0.9 nM and 1.2 nM, respectively .

HY-145373

BMS-986143	Btk	Inflammation/Immunology
BMS-986143 is an orally active, reversible BTK inhibitor with an IC₅₀ of 0.26 nM. BMS-986143 also inhibits TEC, BLK, BMX, TXK FGR, YES1, ITK with IC₅₀s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM,19 nM, 21 nM, respectively. BMS-986143 can be used for the research of autoimmune diseases .

HY-111553

TAS0728	EGFR	Cancer
TAS0728 is a potent, selective, orally active, irreversible and covalent-binding HER2 inhibitor, with an IC₅₀ of 13 nM. TAS0728 also shows IC₅₀s of 4.9, 8.5, 31, 65, 33, 25 and 86 nM for *BMX、HER4、BLK、EGFR、JAK3、SLK* and LOK respectively. Furthermore, TAS0728 exhibits robust and sustained inhibition of the phosphorylation of HER2HER3, and downstream effectors .

Species:	Human (2)
Tag:	His (1) Tag Free (1)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P701711

	BMX Protein, Human (Sf9) BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38	Human	Sf9 insect cells
	BMX proteins are nonreceptor tyrosine kinases that centrally regulate various signaling pathways that control actin dynamics, migration, proliferation, and survival. BMX participates in signal transduction of multiple receptors such as integrins, growth factor receptors, and cytokine receptors, induces BCAR1 tyrosine phosphorylation, and plays a key role in TNF-induced angiogenesis. BMX Protein, Human (Sf9) is the recombinant human-derived BMX protein, expressed by Sf9 insect cells , with tag free. The total length of BMX Protein, Human (Sf9) is 265 a.a., .

HY-P701712

	BMX Protein, Human (Sf9, His) BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38	Human	Sf9 insect cells
	BMX proteins are nonreceptor tyrosine kinases that centrally regulate various signaling pathways that control actin dynamics, migration, proliferation, and survival. BMX participates in signal transduction of multiple receptors such as integrins, growth factor receptors, and cytokine receptors, induces BCAR1 tyrosine phosphorylation, and plays a key role in TNF-induced angiogenesis. BMX Protein, Human (Sf9, His) is the recombinant human-derived BMX protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of BMX Protein, Human (Sf9, His) is 265 a.a., .

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BMX Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
BMX Human Pre-designed siRNA Set A contains three designed siRNAs for BMX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bmx Mouse Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
Bmx Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bmx gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bmx Rat Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
Bmx Rat Pre-designed siRNA Set A contains three designed siRNAs for Bmx gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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