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Results for "

Bufadienolides

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

13

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7994
    Hellebrigenol

    		Others Cancer
    Hellebrigenol is a metabolite of bufadienolides with antitumor activity .
    Hellebrigenol
  • HY-N4255
    Resibufagin

    		Others Cancer
    Resibufagin is a kind of bufadienolide isolated from the venom of Bufo bufo gargarizans, has anti-tumor activities .
    Resibufagin
  • HY-122401
    Daigremontianin

    		Insecticide Infection
    Daigremontianin is an insecticidal bufadienolide that can be isolated from K. daigremontiana x tubiflora. Daigremontianin shows insecticidal activity for silkworm .
    Daigremontianin
  • HY-N13289
    12β-Hydroxyresibufogenin

    		Others Cancer
    12β-Hydroxyresibufogenin is a bufadienolide, which shows significant inhibitory activities against cancer cell lines .
    12β-Hydroxyresibufogenin
  • HY-N8695
    1β-Hydroxybufalin

    		Others Cancer
    1β-Hydroxybufalin is a bufadienolide that can be isolated from Ch’an Su. 1β-Hydroxybufalin inhibits cancer cell growth .
    1β-Hydroxybufalin
  • HY-N6575
    7β-Hydroxybufalin

    		Glycosidase Cholinesterase (ChE) Metabolic Disease
    7β-Hydroxybufalin is a bufadienolide. 7β-Hydroxybufalin can be isolated from the venom of Bufo bufo gargarizans. 7β-Hydroxybufalin inhibits α-glucosidase and acetylcholinesterase .
    7β-Hydroxybufalin
  • HY-129236
    Hellebrin

    		Na+/K+ ATPase Apoptosis Cancer
    Hellebrin is a bufadienolide compound extracted from plants that can inhibit tumor cell growth. Hellebrigenin shows potential in overcoming cancer cells' resistance to apoptosis stimuli and has also demonstrated anti-proliferation effects in multidrug-resistant (MDR) cancer cell models. Hellebrin can act on Na+/K+-ATPase to regulate intracellular signaling pathways .
    Hellebrin
  • HY-N7017
    19-Oxocinobufagin

    		Others Metabolic Disease
    19-Oxocinobufagin is a bufadienolide in toad venom .
    19-Oxocinobufagin
  • HY-N6898
    3-O-Acetylbufotalin

    		Others Cancer
    3-O-Acetylbufotalin is a derivate of bufadienolide, with anti-cancer activity .
    3-O-Acetylbufotalin
  • HY-N12167
    3-epi-Bufalin

    		Others Others
    3-epi-Bufalin (compound 2a) is the microbial transformation product of bufadienolide .
    3-epi-Bufalin
  • HY-N13077
    3-Oxo-resibufogenin

    		Others Others
    3-Oxo-resibufogenin is an important bufadienolide with significant biological activity and potential anti-cancer properties .
    3-Oxo-resibufogenin
  • HY-N7019
    19-Hydroxybufalin

    		Others Cancer
    19-Hydroxybufalin is a bufadienolide, inhibits epithelial-mesenchymal transition and attenuates the migration and invasion of PC3 cells .
    19-Hydroxybufalin
  • HY-N0876
    Arenobufagin
    3 Publications Verification

    		 Others Cancer
    Arenobufagin is a natural bufadienolide from toad venom; has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells.
    Arenobufagin
  • HY-N0880
    Cinobufotalin
    3 Publications Verification

    		 Others Cancer
    Cinobufotalin is a cardiotonic steroids or bufadienolides, is extracted from the skin secretions of the giant toads. Cinobufotalin has been used as a cardiotonic, diuretic and a hemostatic agent, Cinobufotalin is also a potential anti-lung cancer agent .
    Cinobufotalin
  • HY-N6576
    Hellebrigenin

    		Apoptosis Cancer
    Hellebrigenin, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis.
    Hellebrigenin
  • HY-N7020
    Cinobufaginol

    		Others Cancer
    Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively .
    Cinobufaginol

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