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  3. Molecular Interaction Assay Service

Molecular Interaction Assay Service

Affinity is a crucial parameter for assessing molecular interactions and serves as an essential key in identifying biological processes and drug discovery. To evaluating drug efficacy and the stability of biological macromolecules and their complexes, comprehensive studies encompassing kinetics, thermodynamics, and thermal stability is required, focusing on binding occurrence, binding speed, and binding strength. MCE offers a professional molecular interaction detection platform including Surface Plasmon Resonance (SPR), Bio - Layer Interferometry (BLI), Isothermal Titration Calorimetry (ITC), Microscale Thermophoresis (MST) and Nano Differential Scanning Fluorimetry (nanoDSF). Coupled with professional services of virtual screening ,protein expression and purification, we provide a one-stop solution for drug discovery!

Key features and Compatible Sample Types

Method Key features Results Applicable
sample types
SPR Label-Free Detection
Real-Time Monitoring
High Sensitivity
Low sample consumption
High-Throughput Detection
KD
Ka (Kon)
Kd (Koff)
Proteins
DNA/RNA
Lipids
Polysaccharides
Peptides
Small molecules
Cell Lysate
……
MST Low sample consumption
Short measurement time
Analysis in complex buffers
No need for sample immobilization
High sample compatibility
KD
BLI Label-free detection
Low sample consumption with high
sensitivity
Real-Time Monitoring
Wide range of applications
High-throughput detection
KD
Ka (Kon)
Kd (Koff)
ITC No fluorescent labeling or
immobilization required for samples
High sensitivity and precision
Thermodynamic properties can be measured
KD
n (stoichiometry)
ΔH (enthalpy)
ΔS (entropy)
nanoDSF No fluorescent labeling or
immobilization required for samples
High throughput
Low sample consumption
Tm
MCE
Advantages
Advanced Instrumentation
and Equipment
Professional
Technical Team
Comprehensive
Service Process
Customized
Solutions Offering
Online Consulting
Molecular Interaction Assay Service requires evaluation to determine the appropriate scheme and pricing. For additional information about service price andtechnical specifics, please send an email to sales@MedChemExpress.com or contact the sales staff of MedChemExpress directly.
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Molecular Interaction Assay Service

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