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CCNT1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (2)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

SEC inhibitor KL-1 1 Publications Verification KL-1	Apoptosis	Cancer
SEC inhibitor KL-1 (KL-1) is a peptide-like lead compound that is an effective selective SEC inhibitor. SEC inhibitor KL-1 promotes apoptosis and has anti-tumor activity. SEC inhibitor KL-1 doses dependently inhibits the AFF4-CCNT1 interaction, with a Ki value of 3.48 μM ^[1] .

SEC inhibitor KL-2 1 Publications Verification KL-2	Others	Cancer
SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-2 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 1.50 μM ^[1].

CCNT1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CCNT1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCNT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCNT1 Human Pre-designed siRNA Set A CCNT1 Human Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source

	*CDK9-CCNT1* Heterodimer Protein, Human (Sf9)** CDK9; CCNT1; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-T1; CycT1; Cyclin-T	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT1 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNT1 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

	CCNT1 Protein, Human Cyclin-T1; CCNT1; Homo sapiens; Human; Cyclin	Human	E. coli
	CCNT1 Protein, Human is the recombinant human-derived CCNT1, expressed by E. coli , with tag Free labeled tag. The total length of CCNT1 Protein, Human is 259 a.a.,

	*CDK12-CCNT1* Protein, Human (Active, Sf9, GST, His, Flag)** CRK7; CRKRS; KIAA0904	Human	Sf9 insect cells

	*CDK13-CCNT1* Protein, Human (Active, Sf9, GST, His, Flag)** CDC2L; CDC2L5; CHED; KIAA1791	Human	Sf9 insect cells

	*CDK9-CCNT1* Protein, Human (sf9, GST, His)** CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT1 Protein, Human (sf9, GST, His) is the recombinant human-derived CDK9-CCNT1, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. ,

	*CDK12-CCNT1* Protein, Human (sf9, GST, Flag, His)** CDK12; CCNK; Cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; Cyclin-K	Human	Sf9 insect cells
	The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets "Ser-5" phosphorylated at "Ser-7" in the CTD repeat and can also target "Ser-2". CDK12-CCNT1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK12-CCNT1, expressed by Sf9 insect cells , with N-His, N-GST, N-Flag labeled tag. ,

	*CDK13-CCNT1* Protein, Human (sf9, GST, Flag, His)** CDK13; cyclin-dependent kinase 13; CDC2L5, cell division cycle 2 like 5 (cholinesterase related cell division controller); CDC2L; CHED; cholinesterase related cell division controller; KIAA1791; CDC2-related protein kinase 5; cell division protein kinase 13; cell division cycle 2-like protein kinase 5; cholinesterase-related cell division controller; CDC2L5; hCDK13; FLJ35215	Human	Sf9 insect cells
	CDK13-CCNT1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK13-CCNT1, expressed by Sf9 insect cells , with N-His, N-Flag, N-GST labeled tag. ,

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CCNT1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
CCNT1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCNT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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