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Results for "

CHIT1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-137464A
    OATD-01
    1 Publications Verification

    		 Others Inflammation/Immunology
    OATD-01 is a highly potent, first-in-class, orally active and selective chitinase inhibitor with low nanomolar activity toward CHIT1 (hCHIT1,IC50=23 nM). OATD-01 shows excellect PK profile in multiple species and is selectivity against a panel of other off-targets. OATD-01 exhibits significant antifibrotic efficacy in vivo and can be used for pulmonary fibrosis (IPF) research [1].
    OATD-01
  • HY-RS02632
    CHIT1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CHIT1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHIT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CHIT1 Human Pre-designed siRNA Set A
    CHIT1 Human Pre-designed siRNA Set A
  • HY-125279
    OAT-2068

    		Others Inflammation/Immunology
    OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC50=29 nM) and displays 143-fold selectivity over m AMCase (IC50=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases [1].
    OAT-2068

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