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Isoforms Recommended:	Caspase 11

Results for "

Caspase-11

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Caspase (3) Apoptosis (2) Fluorescent Dye (1) Lipoxygenase (2) Pyroptosis (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (3)

4

Inhibitors & Agonists

1

Peptides

2

Natural
Products

2

Antibodies

Targets Recommended: Caspase 11β-HSD SHP2

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Wedelolactone 15+ Cited Publications	Caspase Lipoxygenase Apoptosis	Inflammation/Immunology Cancer
Wedelolactone suppresses LPS-induced *caspase-11* expression by directly inhibits the IKK Complex. Wedelolactone also inhibits 5-lipoxygenase (5-Lox) with an IC₅₀ of 2.5 μM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. Wedelolactone can extract from Eclipta alba, and it can be used for the research of cancer .

Ac-FLTD-CMK 5+ Cited Publications	Caspase Pyroptosis	Inflammation/Immunology
Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against *caspases-1* (IC₅₀ of 46.7 nM), *caspases-4* (IC₅₀ of 1.49 μM), *caspases-5* (IC₅₀ of 329 nM), and *caspases-11* , but not the apoptotic caspases such as caspase-3 .

Ac-YEVD-AMC	Fluorescent Dye	Others
Ac-YEVD-AMC is a fluorescent substrate of *caspase-1/11*. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate .

Wedelolactone (Standard)	Caspase Lipoxygenase Apoptosis	Inflammation/Immunology Cancer
Wedelolactone (Standard) is the analytical standard of Wedelolactone. This product is intended for research and analytical applications. Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibits the IKK Complex. Wedelolactone also inhibits 5-lipoxygenase (5-Lox) with an IC50 of 2.5 μM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. Wedelolactone can extract from Eclipta alba, and it can be used for the research of cancer .

Cat. No.	Product Name	Target	Research Area

Ac-YEVD-AMC	Fluorescent Dye	Others
Ac-YEVD-AMC is a fluorescent substrate of *caspase-1/11*. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate .

Cat. No.	Compare	Product Name	Application	Reactivity

	Caspase 11 Antibody Caspl; ich-3; CASP-4; Casp11; CASP-11	WB, IP	Human, Mouse, Rat
	Caspase 11 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Caspase 11. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

	CASP4 Antibody Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-11; CASP-11; Protease ICH-3; Apoptosis related cysteine peptidase; Apoptotic cysteine protease Mih1/TX; CASP 4; CASP 4; CASP-4; CASP4; CASP4_HUMAN; CASP4_MOUSE; Caspase 4 apoptosis related cysteine peptidase; Caspase-4 subunit 2; Caspase4; ICE(rel) II; ICE(rel)-II; ICE(rel)II; ICEREL II; ICERELII; ICH 2; ICH 2 protease; ICH2; Mih1/TX; Mih1/TX; Protease ICH-2; Protease TX; TX; TX protease; EC:3.4.22.64.	WB, ELISA	Human, Rat
	CASP4 Antibody is a biotin-conjugated non-conjugated IgG antibody, targeting CASP4, with a predicted molecular weight of 43 kDa. CASP4 Antibody can be used for WB, ELISA experiment in human and rat background.

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