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FASLG

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By Targets:	Small Interfering RNA (siRNA) (1) TNF Receptor (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

2

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Natural
Products

9

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1

Antibodies

1

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Asunercept APG101; CAN008	TNF Receptor	Inflammation/Immunology Cancer
Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD) .

FASLG Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FASLG Human Pre-designed siRNA Set A contains three designed siRNAs for FASLG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FASLG Human Pre-designed siRNA Set A FASLG Human Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

Asunercept APG101; CAN008	TNF Receptor	Inflammation/Immunology Cancer
Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD) .

Cat. No.	Product Name	Category	Target	Chemical Structure

Asunercept APG101; CAN008	Classification of Application Fields Disease Research Fields Cancer	TNF Receptor
Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD) .

Species:	Human (4) Mouse (4) Rat (1)
Tag:	His (8) Fc (1)
Source:	HEK293 (4) P. pastoris (3) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P700176AF

	Animal-Free Fas Ligand Protein, Mouse (His) soluble Fas Ligand (sFasL); TNFSF6; CD95L; Apo I Ligand; APTL; APT1LG1; CD178; Fas-Lg; Tnfs; Tnlg1a; gld	Mouse	E. coli
	The cytoplasmic form of Fas ligand protein exerts powerful effects by inhibiting gene transcription. This protein plays a crucial role in regulating cellular processes by inhibiting the expression of specific genes. Animal-Free Fas Ligand Protein, Mouse (His) is the recombinant mouse-derived animal-FreeFas Ligand protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free Fas Ligand Protein, Mouse (His) is 152 a.a., with molecular weight of ~18.14 kDa.

	FASLG Protein, Human (His) Apoptosis antigen ligand ; APTLCD95 ligand ; CD95-LFas antigen ligand ; Fas ligand ; FasL; CD178	Human	E. coli
	FASLG protein binds to TNFRSF6/FAS and triggers apoptotic signals. FASLG Protein, Human (His) is the recombinant human-derived FASLG protein, expressed by E. coli , with N-6*His labeled tag. The total length of FASLG Protein, Human (His) is 179 a.a., with molecular weight of 26 kDa.

	Fas/CD95 Protein, Mouse (HEK293, Fc) FASLG receptor; CD95; APT1; FAS1; TNFRSF6; FAS; ALPS1A; APO1; FASTM; FasR	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, Fc) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal hFc-tag.

	Fas/CD95 Protein, Mouse (HEK293, His) rMuTumor necrosis factor receptor superfamily member 6//TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD95; Fas; TNFRSF6	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, His) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal 6*His-tag.

	Fas/CD95 Protein, Human (HEK293, His) rHuTumor necrosis factor receptor superfamily member 6/TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; APT1; FAS1; TNFRSF6 and FAS	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, His) has a full length of 147 amino acids (Q26-N173), produced in HEK293 cells with C-terminal 6*His-tag.

	Fas Ligand Protein, Human (HEK293, His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; Fas ligand; FasL; CD178; TNFSF6	Human	HEK293
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Fas Ligand Protein, Human (HEK293, His) has a total length of 148 amino acids (P134-L281), is expressed in HEK392 cells with N-terminal 6*His-tag.

	FASLG Protein, Human (P. pastoris, His) Apoptosis antigen ligand ; APTLCD95 ligand ; CD95-LFas antigen ligand ; Fas ligand ; FasL; CD178	Human	P. pastoris
	FASLG protein binds to TNFRSF6/FAS and triggers apoptotic signals. FASLG Protein, Human (P. pastoris, His) is the recombinant human-derived FASLG protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of FASLG Protein, Human (P. pastoris, His) is 179 a.a., with molecular weight of 22.4 kDa.

	Fas Ligand Protein, Rat (P.pastoris, His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; Fas ligand; FasL; CD178; TNFSF6	Rat	P. pastoris
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Rat Fas Ligand exhibits 4 isoforms, the soluble form (127-278 a.a.) involves in germ cell apoptosis in testis of rats undergoing autoimmune orchitis. Fas Ligand Protein, Rat (P.pastoris, His) has a total length of 175 amino acids (L104-L278), is expressed in P.pastoris cells with N-terminal His-tag.

	Fas Ligand Protein, Mouse (P.pastoris, His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; Fas ligand; FasL; CD178; TNFSF6	Mouse	P. pastoris
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Mouse Fas Ligand has a total length of 279 amino acids (M1-L279), with a TNF_2 domain (144-279 a.a.). Fas Ligand Protein, Mouse (P.pastoris, His) is a recombinant protein expressed in P.pastoris cells with N-terminal His-tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

	Fas Ligand Antibody Tumor necrosis factor ligand superfamily member 6; FASLG; APO1L; Apoptosis (APO 1) antigen ligand 1; Fas-L; Apoptosis antigen ligand 1; APTL; CD178; CD-178; CD 178; CD95L; CD95 ligand; CD95-L; CD95L protein; FAS antigen ligand; Fas L; FASL; Fas ligand (TNF superfamily member 6); Generalized lymphoproliferative disease; TNF superfamily member 6; TNFSF6; TNFL6_HUMAN; Apoptosis antigen ligand; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; FASLG.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF,	Human, Mouse, Rat
	Fas Ligand Antibody is an unconjugated, approximately 31 kDa, rabbit-derived, anti-Fas Ligand polyclonal antibody. Fas Ligand Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: cow background without labeling.

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Cat. No.	Product Name		Classification

FASLG Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
FASLG Human Pre-designed siRNA Set A contains three designed siRNAs for FASLG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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