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Results for "

G12R

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Ras (3)
By Research Areas:	Cancer (3)
Click Chemistry:	Azide (2)

3

Inhibitors & Agonists

2

Recombinant Proteins

2

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*KRas G12R inhibitor 1*	Ras	Cancer
KRas G12R inhibitor 1 (compound 3) is a KRas G12R selective covalent inhibitor that exploits the strong nucleophilicity of mutant cysteines and binds irreversibly in the Switch II region of K-Ras. KRas G12R inhibitor 1 can be used in cancer research .

KRAS inhibitor-24	Ras	Cancer
KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC₅₀ of < 100 nM for KRas G12V, KRas WT and KRas G12R .

KRAS inhibitor-25	Ras	Cancer
KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC₅₀ of < 100 nM against KRas G12V, KRas WT and KRas G12R .

Species:	Human (2)
Tag:	His (2) Avi (2)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source

	*HLA-A1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi)** MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGARGVGK peptide. HLA-A*1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

	*HLA-A1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi)** MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD	Human	HEK293
	HLA-A1101as is a key MHCI molecule that presents viral and tumor-derived peptides that direct T cell immune responses against infected or transformed cells. It collaborates with B2M to showcase a diverse peptide library. HLA-A1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293* , with C-Avi, C-His labeled tag and VVVGARGVGK peptide. HLA-A*1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

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Cat. No.	Product Name		Classification

KRAS inhibitor-24		Azide
KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC₅₀ of < 100 nM for KRas G12V, KRas WT and KRas G12R .

KRAS inhibitor-25		Azide
KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC₅₀ of < 100 nM against KRas G12V, KRas WT and KRas G12R .

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