2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. KRAS inhibitor-24

KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R.

For research use only. We do not sell to patients.

KRAS inhibitor-24 Chemical Structure

KRAS inhibitor-24 Chemical Structure

CAS No. : 3030576-47-4

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KRAS inhibitor-24 Related Antibodies

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Description

KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R[1].

IC50 & Target[1].

KRas G12V

< 100 nM (IC50)

K-Ras WT

< 100 nM (IC50)

KRas G12R

< 100 nM (IC50)

Molecular Weight

641.15

Formula

C33H39ClF2N6O3
CAS No.
SMILES

FC1=C(C2=CC(O)=CC(Cl)=C2CCCCC(NCC[C@@]3([H])CN4CCC3)=O)N=CC(C1=N5)=C4N=C5OC[C@@]67N(CCC7)C[C@@H](C6)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS inhibitor-24 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS inhibitor-243030576-47-4KRAS inhibitor24KRAS inhibitor 24RasInhibitorinhibitorinhibit

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HY-159474
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