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HDAC1/6-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162781
    HDAC1/6-IN-2

    		HDAC Cancer
    HDAC1/6-IN-2 (I-c4) is the inhibitor of HDAC1 and HDAC6, with the IC50s of 3.1 nM and 2.95 nM, respectively. HDAC1/6-IN-2 has antitumor activity .
    HDAC1/6-IN-2
  • HY-149718
    Antitumor agent-123

    		JAK HDAC Cancer
    Antitumor agent-123 (Copmound 4d) effectively inhibits multiple kinase targets with anti-cancer effects, including JAK2, JAK3, HDAC1 and HDAC6, with IC50 values of 34.6 and 2.6 μM for JAK2 and JAK3, respectively. Antitumor agent-123 exhibits moderate activity in solid tumor models .
    Antitumor agent-123
  • HY-155523
    Tubulin/HDAC-IN-2

    		Microtubule/Tubulin HDAC Apoptosis Cancer
    Tubulin/HDAC-IN-2 (Compound II-19k) is a dual inhibitor of Tubulin and HDAC, with an IC50 of 0.403 μM, 0.591μM, 3.552μM, 0.459μM for HDAC1/2/3/6. Tubulin/HDAC-IN-2 blocks cell cycle arrest at G2 phase, induces cell apoptosis. Tubulin/HDAC-IN-2 inhibits the growth of hematoma and solid tumor cells, reduces tumor metastasis, and also inhibits tumor growth in a liver tumor allograft mouse model .
    Tubulin/HDAC-IN-2

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