2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC1/6-IN-2

HDAC1/6-IN-2 (I-c4) is the inhibitor of HDAC1 and HDAC6, with the IC50s of 3.1 nM and 2.95 nM, respectively. HDAC1/6-IN-2 has antitumor activity.

For research use only. We do not sell to patients.

HDAC1/6-IN-2 Chemical Structure

HDAC1/6-IN-2 Chemical Structure

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HDAC1/6-IN-2 Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

HDAC1/6-IN-2 (I-c4) is the inhibitor of HDAC1 and HDAC6, with the IC50s of 3.1 nM and 2.95 nM, respectively. HDAC1/6-IN-2 has antitumor activity[1].

IC50 & Target

HDAC6

2.95 nM (IC50)

HDAC1

3.1 nM (IC50)

Molecular Weight

404.39

Formula

C22H17FN4O3
SMILES

O=C(C1=CC(C2=CC=C(C=C2)F)=CN3C1=NC=C3)NCC4=CC=C(C=C4)C(NO)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HDAC1/6-IN-2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC1/6-IN-2HDACHistone deacetylasesMGC-803 cellsH9c2 cellsInhibitorinhibitorinhibit

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