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Lumateperone-</sup>CH<sub>C,d<sub>3</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Dopamine Receptor (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (1) Neurological Disease (1)

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19733S

Lumateperone-13C,d3 tosylate ITI-007-sup>CH<sub>C,d<sub>3sub> tosylate	Isotope-Labeled Compounds Dopamine Receptor 5-HT Receptor	Neurological Disease Cancer
Lumateperone- ¹³C,d₃ (ITI-007- ¹³C,d₃) tosylate is ¹³C and deuterium labeled Lumateperone (tosylate). Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia .

Cat. No.	Product Name	Chemical Structure

HY-19733S

Lumateperone-13C,d3 tosylate
Lumateperone- ¹³C,d₃ (ITI-007- ¹³C,d₃) tosylate is ¹³C and deuterium labeled Lumateperone (tosylate). Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia .

Lumateperone-13C,d3 tosylate

Lumateperone- ¹³C,d₃ (ITI-007- ¹³C,d₃) tosylate is ¹³C and deuterium labeled Lumateperone (tosylate). Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia .

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Lumateperone-</sup>CH<sub>C,d<sub>3</sub>

Inhibitors & Agonists

Isotope-Labeled Compounds