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METTL1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA Methyltransferase (1) METTL3 (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (2)
Oligonucleotides:	siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

METTL1-WDR4-IN-1	METTL3	Cancer
METTL1-WDR4-IN-1 (1) is a *METTL1-WDR4* inhibitor, with an IC₅₀ of 144 μM ^[1].

METTL1-WDR4-IN-2	DNA Methyltransferase	Cancer
METTL1-WDR4-IN-2 (compound 6) is a selective methyltransferase Like 1 (METTL1)-WDR4 inhibitor with an IC₅₀ of 41 μM. METTL1-WDR4-IN-2 shows remarkable selectivity against METTL3-14 and slightly selective also against METTL16 ^[1].

METTL1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
METTL1 Human Pre-designed siRNA Set A contains three designed siRNAs for METTL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

METTL1 Human Pre-designed siRNA Set A METTL1 Human Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source

	METTL1 Protein, Human (His) tRNA (guanine-N(7)-)-methyltransferase; Methyltransferase-like protein 1; METTL1; C12orf1	Human	E. coli
	The METTL1 protein is a catalytic component of the METTL1-WDR4 methyltransferase complex, which promotes the formation of N(7)-methylguanine in tRNA, mRNA, and miRNA. METTL1 Protein, Human (His) is the recombinant human-derived METTL1 protein, expressed by E. coli , with N-His labeled tag.

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Cat. No.	Product Name		Classification

METTL1 Human Pre-designed siRNA Set A		siRNAs
METTL1 Human Pre-designed siRNA Set A contains three designed siRNAs for METTL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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