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Results for "

NOMO-1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16271
    Kevetrin hydrochloride
    1 Publications Verification

    4-Isothioureidobutyronitrile hydrochloride; thioureidobutyronitrile hydrochloride; thioureido butyronitrile hydrochloride

    		 MDM-2/p53 Apoptosis Cancer
    Kevetrin hydrochloride is a potent activator of p53, induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells. Kevetrin a preferential cytotoxic activity against blast cells [1] .
    Kevetrin hydrochloride
  • HY-163677
    ARM165

    		PROTACs PI3K Akt Cancer
    ARM165 is a heterobifunctional molecule. ARM165 degrades the PIK3CG proteins, inhibits PI3Kγ-Akt signaling pathway, and thus exhibits antileukemia efficacy. ARM165 inhibits proliferations of AML cells, with IC50 <1 μM. (Pink: ligand for target protein PI3Kγ inhibitor AZ2 (HY-111570); Black: linker; Blue: ligand for E3 ligase Pomalidomide (HY-10984)) [1]
    ARM165
  • HY-P99272
    Ulocuplumab

    BMS 936564; MDX 1338; Anti-Human CXCR4 Recombinant Antibody

    		 CXCR Cancer
    Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) is a fully human IgG4 anti-CXCR4 antibody. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL). Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models [1] .
    Ulocuplumab
  • HY-RS09422
    NOMO1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    NOMO1 Human Pre-designed siRNA Set A contains three designed siRNAs for NOMO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    NOMO1 Human Pre-designed siRNA Set A
    NOMO1 Human Pre-designed siRNA Set A
  • HY-13498
    BRD-8899

    		STK33 Cancer
    BRD-8899 is a STK33 inhibitor, with an IC50 of 11 nM [1].
    BRD-8899
  • HY-163678
    Pomalidomide-CO-C7-NH-CO-C3-COOH

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-CO-C7-NH-CO-C3-COOH is a conjugate of a ligand for E3 ligase and a linker. Pomalidomide-CO-C7-NH-CO-C3-COOH can be used for synthesis of PROTAC degrader ARM165 (HY-163677) [1].
    Pomalidomide-CO-C7-NH-CO-C3-COOH

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