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Results for "

OSBP

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Natural
Products

1

Isotope-Labeled Compounds

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101213
    OSW-1
    2 Publications Verification

    		 Others Cancer
    OSW-1, isolated from Ornithogalum caudatum, is a specific antagonist of osterol-binding protein (OSBP) and OSBP-related protein 4 (ORP4) with GI50s in the nanomolar range in human cancer lines.
    OSW-1
  • HY-124806
    TTP-8307
    1 Publications Verification

    		 Enterovirus DNA/RNA Synthesis HCV Infection
    TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP) .
    TTP-8307
  • HY-17514
    Itraconazole
    Maximum Cited Publications
    14 Publications Verification

    R51211

    		 Fungal Hedgehog Cytochrome P450 Autophagy Antibiotic Bacterial Infection Cancer
    Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
    Itraconazole
  • HY-17514S2
    Itraconazole-d9

    R51211-d9

    		 Fungal Hedgehog Bacterial Autophagy Cytochrome P450 Antibiotic Infection
    Itraconazole-d9 is the deuterium labeled Itraconazole[1]. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor[2][3][4][5].
    Itraconazole-d9
  • HY-156275
    OSBP-IN-1

    		Others Cancer
    OSBP-IN-1(compound 12) is a Schweinfurthins analogues targeted of oxysterol-binding protein (OSBP). OSBP-IN-1 has antitumor activity .
    OSBP-IN-1
  • HY-RS09835
    OSBP Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    OSBP Human Pre-designed siRNA Set A contains three designed siRNAs for OSBP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    OSBP Human Pre-designed siRNA Set A
    OSBP Human Pre-designed siRNA Set A
  • HY-RS09836
    OSBP2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    OSBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for OSBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    OSBP2 Human Pre-designed siRNA Set A
    OSBP2 Human Pre-designed siRNA Set A
  • HY-163891
    Antifungal agent 107

    		Others Infection
    Antifungal agent 107 (compound b24) is an OSBP inhibitor with antifungal activity. Antifungal agent 107 can be used to control cucumber downy mildew and potato late blight in greenhouse .
    Antifungal agent 107
  • HY-148391
    23-Oxa-OSW-1

    SBF-1

    		 DNA/RNA Synthesis Cancer
    23-Oxa-OSW-1 (SBF-1), a derivative of OSW 1 (HY-101213), is a potent osterol-binding protein (OSBP) inhibitor. 23-Oxa-OSW-1 has antitumor activity .
    23-Oxa-OSW-1
  • HY-17514R
    Itraconazole (Standard)

    		Fungal Hedgehog Cytochrome P450 Autophagy Antibiotic Bacterial Infection Cancer
    Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
    Itraconazole (Standard)

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