2. Anti-infection Stem Cell/Wnt Metabolic Enzyme/Protease Autophagy
  3. Fungal Hedgehog Cytochrome P450 Autophagy Antibiotic Bacterial
  4. Itraconazole (Standard)

Itraconazole (Standard) 

Cat. No.: HY-17514R Purity: ≥98%
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Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.

For research use only. We do not sell to patients.

Itraconazole (Standard) Chemical Structure

Itraconazole (Standard) Chemical Structure

CAS No. : 84625-61-6

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Description
Molecular Weight

705.63

Formula

C₃₅H₃₈Cl₂N₈O₄
CAS No.
SMILES

ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(C)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7
Initial Source
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Itraconazole (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Itraconazole (Standard)84625-61-6FungalHedgehogCytochrome P450AutophagyAntibioticBacterialCYPsTriazoleantifungalHhanticancerCYP-450antiangiogenic14α-demethylaselanosterolergosterolInhibitorinhibitorinhibit

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