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Puromycin

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By Targets:	Aminopeptidase (1) Antibiotic (6) Apoptosis (1) Bacterial (6) Dipeptidyl Peptidase (1) Isotope-Labeled Compounds (2) Parasite (3)
By Research Areas:	Cancer (2) Infection (6) Neurological Disease (1)
Click Chemistry:	Alkynes (1)

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1743

*Puromycin* Maximum Cited Publications 191 Publications Verification CL13900	Bacterial Antibiotic Parasite	Infection
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-15695

Puromycin aminonucleoside 25+ Cited Publications NSC 3056	Bacterial Apoptosis Dipeptidyl Peptidase Aminopeptidase Antibiotic	Cancer
Puromycin aminonucleoside (NSC 3056) is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models . Puromycin aminonucleoside induces apoptosis . Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase . Puromycin aminonucleoside induces secretion of cell migrasome .

HY-B1743S

Puromycin-d3 3 Publications Verification CL13900-d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Puromycin-d₃ is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743A

Puromycin dihydrochloride Maximum Cited Publications 191 Publications Verification CL13900 dihydrochloride	Bacterial Antibiotic Parasite	Infection Cancer
Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-B1743AS

Puromycin-d3 dihydrochloride 3 Publications Verification CL13900-d₃ dihydrochloride	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Puromycin-d₃ (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].

HY-148865

Puromycin-bis(PEG2-amide)-Biotin	Others	Others
Puromycin-bis(PEG2-amide)-Biotin is used for single-cell translatome sequencing .

HY-B1743AR

Puromycin dihydrochloride (Standard)	Bacterial Antibiotic Parasite	Infection
Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride). This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-158410

PSA-IN-1	Others	Neurological Disease
PSA-IN-1 (compound 19) is a puromycin sensitive aminopeptidase (PSA) inhibitor with IC₅₀ at 7 nM. PSA-IN-1 has analgesic activity .

HY-110271

N-Acetylpuromycin	Others	Others
N-Acetylpuromycin is a inactive form of the antibiotic puromycin. N-Acetylpuromycin is the last intermediate of the puromycin antibiotic biosynthetic pathway in Streptomyces alboniger .

HY-119673

Lincophenicol	Others	Others
Lincophenicol is a hybrid antibiotic that has the activity of inhibiting the puromycin reaction catalyzed by Escherichia coli ribosomal peptidyl transferase and also inhibits the binding of specific compounds to the Escherichia coli ribosome.

HY-122430

Rosaramicin	Others	Others
Rosaramicin is a macrolide antibiotic that binds to the ribosomal P site and produces a synergistic effect with puromycin. This synergistic effect may be related to the interaction between the A and P sites. At the same time, its binding activity is affected by multiple substances.

HY-129407

AAF-CMK TFA Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II	Others	Infection
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

HY-135534

Lysine 4-nitroanilide	Others	Others
Lysine 4-nitroanilide is an amino acid derivative used in studies of enzymology. Two major arylamidase activities were isolated from particle-free supernatant of rat heart by DEAE-Sephadex chromatography. Although both enzymes hydrolyze L-leucine 4-nitroanilide, only the peak II enzyme does so. A third, minor peak (Ia) contains the enzyme active primarily toward L-lysine 4-nitroanilide. The molecular weights of the enzymes in peaks I and II are approximately 257,000 and 105,000, respectively. The optimum pH for the peak I enzyme is approximately pH 7.0, while that for the peak II enzyme is between 7.0 and 8.0. Both enzymes are inhibited by puromycin, p-hydroxymercurybenzoate, catechol, and divalent metal ions. Addition of dithiothreitol stimulates both activities. Dialysis against catechol resulted in inhibition of both peak I and II enzymes, but dialysis against EDTA inhibited only the peak II enzyme.

Cat. No.	Product Name

HY-K1057

Puromycin, Sterile 10+ Cited Publications
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1743

*Puromycin* 190+ Cited Publications CL13900	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic Parasite
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743A

Puromycin dihydrochloride 190+ Cited Publications CL13900 dihydrochloride	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Resistance Selection Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic Parasite
Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-B1743AR

Puromycin dihydrochloride (Standard)	Structural Classification Microorganisms Antibiotics Resistance Selection Source classification Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic Parasite
Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride). This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

Cat. No.	Product Name	Chemical Structure

HY-B1743S

Puromycin-d3 3 Publications Verification
Puromycin-d₃ is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743AS

Puromycin-d3 dihydrochloride 3 Publications Verification
Puromycin-d₃ (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82414

	ERAP1 Antibody (YA2159) ERAP1; APPILS; ARTS1; KIAA0525; Endoplasmic reticulum aminopeptidase 1; ARTS-1; Adipocyte-derived leucine aminopeptidase; A-LAP; Aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP; Type 1 tumor necrosis facto	WB, IHC-P	Human, Rat
	ERAP1 Antibody (YA2159) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2159), targeting ERAP1, with a predicted molecular weight of 107 kDa (observed band size: 107 kDa). ERAP1 Antibody (YA2159) can be used for WB, IHC-P experiment in human, rat background.

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HY-15680

O-Propargyl-Puromycin 15+ Cited Publications		Alkynes
O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Puromycin

Inhibitors & Agonists

MCE Kits

NaturalProducts

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Natural
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