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Results for "

SMARCA2-IN-9

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

2

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161881
    SMARCA2-IN-9

    		Epigenetic Reader Domain Cancer
    SMARCA2-IN-9 (compound 11) is a SMARCA2, PBRM1 bromodomains 2 (PBRM1(2)), and PBRM1 bromodomains 5 (PBRM1(5)) inhibitor with Kd values of 1.6 μM, 2.5 μM, and 3.95 μM, respectively .
    SMARCA2-IN-9
  • HY-159448
    PROTAC SMARCA2 degrader-4

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC SMARCA2 degrader-4 (Compound I-424) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2. PROTAC SMARCA2 degrader-9 degrades SMARCA2 in MV411 and in A549 with DC50 <100 nM, degrades SMARCA4 in MV411 with DC50 >1 μM . (Pink: Ligand for target protein (HY-159531); Black: Linker (HY-159532); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))
    PROTAC SMARCA2 degrader-4
  • HY-159461
    PROTAC SMARCA2/4-degrader-9

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC SMARCA2/4-degrader-9 (Compound I-503) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2 degrader-9 degrades SMARCA2 in MV411 and in A549 with DC50 <100 nM, degrades SMARCA4 in MV411 with DC50 <100 nM . (Pink: Ligand for target protein (HY-159545); Black: Linker (HY-W006635); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))
    PROTAC SMARCA2/4-degrader-9

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