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Sarcosine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Biochemical Assay Reagents (1) Endogenous Metabolite (7) GlyT (3) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (3) Metabolic Disease (2)

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101037

*Sarcosine* N-Methylglycine; Sarcosin	Endogenous Metabolite GlyT	Cancer
Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia .

HY-P2861

Sarcosine oxidase, Bacillus SAO	Endogenous Metabolite	Others
Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H₂O₂, 5,10-CH₂-tetrahydrofolate, which are often used in biochemical reactions .

HY-101037S1

Sarcosine-d3 N-Methylglycine-d₃; Sarcosin-d₃	Isotope-Labeled Compounds Endogenous Metabolite GlyT	Cancer
Sarcosine-d₃ is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

HY-101037S

Sarcosine-15N N-Methylglycine-¹⁵N; Sarcosin-¹⁵N	Endogenous Metabolite GlyT	Cancer
Sarcosine- ¹⁵N is the ¹⁵N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

HY-P2893

Creatinase, Actinobacteria Creatine amidohydrolase	Endogenous Metabolite	Others
Creatinase, Actinobacteria (Creatine amidohydrolase) is a hydrolase that catalyzes the hydrolysis of creatine into sarcosine and urea, and plays an important role in the enzymatic determination of creatinine concentration .

HY-164166

Fmoc-Sar-Sar-Sar-OH	Biochemical Assay Reagents	Others
Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of four sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of drug-peptide ligand conjugates .

HY-P2838

Creatininase, Microorganism Creatinine amidohydrolase; CAH	Endogenous Metabolite	Metabolic Disease
Creatininase, Microorganism (Creatinine amidohydrolase; CAH), namely creatinine amidohydrolase, from Pseudomonas putida, is a homohexameric enzyme commonly used in biochemical research. Creatininase acts on carbon-nitrogen bonds other than peptide bonds, and can catalyze the hydrolysis of creatinine to creatine, which can then be metabolized by creatinase to urea and sarcosine .

HY-Y1144

Sarcosine ethyl ester hydrochloride N-[(Ethoxycarbonyl)methyl]-N-methylamine hydrochloride; Sacrosine ethyl ester hydrochloride	Amino Acid Derivatives	Others
Sarcosine ethyl ester hydrochloride is a Glycine (HY-Y0966) derivative .

HY-P2893A

Creatinase (Recombinant) Creatine amidinohydrolase	Endogenous Metabolite	Metabolic Disease
Creatinase (Recombinant) is a hydrolase responsible for catalyzing the hydrolysis of creatine (HY-W010388) into sarcosine (HY-101037) and urea (HY-Y0271). Creatinase (Recombinant) can be used in conjunction with creatinine deiminase (HY-P2838) and sarcosine oxidase (HY-P2861) in an enzyme cascade reaction to measure creatinine (HY-B0504) levels in blood and urine. Creatinase (Recombinant) is the rate-limiting enzyme in this enzymatic cascade, and the enzymatic quantification of creatinine is an important method for evaluating kidney function .

Cat. No.	Product Name	Target	Research Area

HY-164166

Fmoc-Sar-Sar-Sar-OH	Biochemical Assay Reagents	Others
Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of four sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of drug-peptide ligand conjugates .

HY-Y1144

Sarcosine ethyl ester hydrochloride N-[(Ethoxycarbonyl)methyl]-N-methylamine hydrochloride; Sacrosine ethyl ester hydrochloride	Amino Acid Derivatives	Others
Sarcosine ethyl ester hydrochloride is a Glycine (HY-Y0966) derivative .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101037

*Sarcosine* N-Methylglycine; Sarcosin	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Classification of Application Fields Source classification Disease markers Endocrine diseases Amino acids Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite GlyT
Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia .

Tag:	His (1) Tag Free (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P702177

	*monomeric sarcosine* oxidase Protein, Bacillus sp.** soxA; Monomeric Sarcosine oxidase; MSOX	Others	E. coli
	Monomeric sarcosine oxidase protein is pivotal in cellular metabolism, catalyzing the oxidative demethylation of sarcosine. Its enzymatic activity facilitates the removal of a methyl group from sarcosine, contributing to metabolic transformations in various biochemical pathways. This process underscores the protein's significance in regulating cellular methyl group transfers, emphasizing its crucial role in maintaining metabolic homeostasis. monomeric sarcosine oxidase Protein, Bacillus sp. is the recombinant monomeric sarcosine oxidase protein, expressed by E. coli , with tag free. The total length of monomeric sarcosine oxidase Protein, Bacillus sp. is 387 a.a., .

HY-P702178

	*monomeric sarcosine* oxidase Protein, Bacillus sp. (His)** soxA; Monomeric Sarcosine oxidase; MSOX	Others	E. coli
	Monomeric sarcosine oxidase protein is pivotal in cellular metabolism, catalyzing the oxidative demethylation of sarcosine. Its enzymatic activity facilitates the removal of a methyl group from sarcosine, contributing to metabolic transformations in various biochemical pathways. This process underscores the protein's significance in regulating cellular methyl group transfers, emphasizing its crucial role in maintaining metabolic homeostasis. monomeric sarcosine oxidase Protein, Bacillus sp. (His) is the recombinant monomeric sarcosine oxidase protein, expressed by E. coli , with N-6*His labeled tag. The total length of monomeric sarcosine oxidase Protein, Bacillus sp. (His) is 387 a.a., .

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Cat. No.	Product Name	Chemical Structure

HY-101037S1

Sarcosine-d3
Sarcosine-d₃ is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

Sarcosine-d3

Sarcosine-d₃ is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

HY-101037S

Sarcosine-15N
Sarcosine- ¹⁵N is the ¹⁵N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

Sarcosine-15N

Sarcosine- ¹⁵N is the ¹⁵N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

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