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Results for "

U2AF

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Natural
Products

4

Recombinant Proteins

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153736
    NSC 194308

    		Others Cancer
    NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2). NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell death in leukemia cell lines containing spliceosome mutations .
    NSC 194308
  • HY-RS15313
    U2AF1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    U2AF1 Human Pre-designed siRNA Set A contains three designed siRNAs for U2AF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    U2AF1 Human Pre-designed siRNA Set A
    U2AF1 Human Pre-designed siRNA Set A
  • HY-RS15314
    U2AF2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    U2AF2 Human Pre-designed siRNA Set A contains three designed siRNAs for U2AF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    U2AF2 Human Pre-designed siRNA Set A
    U2AF2 Human Pre-designed siRNA Set A
  • HY-148384
    UHMCP1

    		Others Cancer
    UHMCP1 is a chemical probe of U2AF homology motifs (UHM) with a Kd of 79 μM. UHMCP1 prevents the SF3b155/U2AF65 interaction, impacts RNA splicing and cell viability. UHMCP1 has potential anticancer properties .
    UHMCP1
  • HY-148384A
    UHMCP1 dihydrochloride

    		Others Cancer
    UHMCP1 dihydrochloride is a potent UHM domain splicing inhibitor with a Kd value of 79 µM. UHMCP1 dihydrochloride prevents the SF3b155/U2AF 65 interaction. UHMCP1 dihydrochloride impacts cell viability and RNA splicing .
    UHMCP1 dihydrochloride
  • HY-139104
    Thailanstatin D

    		DNA/RNA Synthesis Apoptosis Cancer
    Thailanstatin D, an analogue of Thailanstatin A, is able to inhibit AR-V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3' splice site. Thailanstatin D exhibits a potent tumor inhibitory effect on human CRPC xenografts leading to cell apoptosis .
    Thailanstatin D

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