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Results for "

Urea Transporter

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Recombinant Proteins

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162864
    JX237

    		Endogenous Metabolite Metabolic Disease
    JX237 is an inhibitor of the epithelial neutral amino acid transporter B 0AT1 (SLC6A19) with an IC50 value of 31 nM. JX237 is the main transporter for the absorption of neutral amino acids in the intestines and their reabsorption in the kidneys. By inhibiting B 0AT1, JX237 can help normalize elevated plasma amino acids in rare amino acid metabolic disorders like phenylketonuria and urea cycle disorders .
    JX237
  • HY-155642
    PU-48

    		Urea Transporter Metabolic Disease
    PU-48 is a potent urea transporters A (UT-A) inhibitor (IC50=0.32 μM). PU-48 has a good diuretic effect in mouse models, and shows little or no cytotoxicity. PU-48 has the potential to be developed as a diuretic .
    PU-48
  • HY-128129
    UT-B-IN-1

    		Urea Transporter Metabolic Disease
    UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research .
    UT-B-IN-1
  • HY-131382
    UTA1inh-C1

    		Urea Transporter Metabolic Disease
    UTA1inh-C1 is a urea transporter (UT-A) inhibitor with IC50 of 4.2 μM .
    UTA1inh-C1

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