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Results for "

caffeine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Biochemical Assay Reagents (2) Drug Metabolite (5) Endogenous Metabolite (16) Fluorescent Dye (1) iGluR (1) Isotope-Labeled Compounds (3) Monoamine Oxidase (1) nAChR (1) Sodium Channel (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Inflammation/Immunology (4) Neurological Disease (10)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D2264

Caffeine orange	Fluorescent Dye	Others
Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

HY-103164

(E)-8-(3-Chlorostyryl)caffeine	Adenosine Receptor Monoamine Oxidase	Neurological Disease
(E)-8-(3-Chlorostyryl)caffeine is a selective adenosine A_2A receptor antagonist. (E)-8-(3-Chlorostyryl)caffeine inhibits monoamine oxidase B (MAO-B) with a K_i value of 70 nM by a pathway that is independent of its actions on the A_2A receptor. (E)-8-(3-Chlorostyryl)caffeine has the potential for Parkinson's disease research .

HY-W016415

7-Methyluric acid	Biochemical Assay Reagents Endogenous Metabolite	Others
7-Methyluric acid is a metabolite of caffeine. 7-Methyluric acid can be detected in urine .

HY-113327

1,3,7-Trimethyluric acid	Endogenous Metabolite	Cancer
1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort .

HY-W008449

1-Methylxanthine	Drug Metabolite Endogenous Metabolite	Cancer
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) . 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-103164A

8-(3-Chlorostyryl)caffeine CSC	Others	Neurological Disease
8-(3-Chlorostyryl)caffeine (CSC) is an adenosine antagonist with selective activity at the A2a adenosine receptor. 8-(3-Chlorostyryl)caffeine showed 520-fold selectivity in radioligand binding experiments in rat brain. Antagonism of adenylylase by 8-(3-Chlorostyryl)caffeine shows 22-fold selectivity in rat chromaffin cells When 8-(3-Chlorostyryl)caffeine is co-administered with the A1-selective antagonist CPX, It can also further increase exercise activity. 8-(3-Chlorostyryl)caffeine exhibits good MAO-B inhibitory activity in primate mitochondria. 8-(3-Chlorostyryl)caffeine also has excellent A2A receptor affinity .

HY-126061

1,7-Dimethyluric acid	Endogenous Metabolite	Neurological Disease
1,7-Dimethyluric acid is the metabolite of caffeine .

HY-N7564

Methylliberine	Others	Cardiovascular Disease
Methylliberine is a purine alkaloid metabolite of caffeine with oral activity .

HY-113118

AAMU 5-Acetylamino-6-amino-3-methyluracil	Endogenous Metabolite	Others
AAMU (5-Acetylamino-6-amino-3-methyluracil) is the main metabolite of caffeine in the human body .

HY-W008449R

1-Methylxanthine (Standard)	Drug Metabolite Endogenous Metabolite	Cancer
1-Methylxanthine (Standard) is the analytical standard of 1-Methylxanthine. This product is intended for research and analytical applications. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) . 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-W008449S2

1-Methylxanthine-d3	Drug Metabolite Endogenous Metabolite Isotope-Labeled Compounds	Cancer
1-Methylxanthine-d₃ is deuterated labeled 1-Methylxanthine (HY-W008449). 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) . 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-126061S

1,7-Dimethyluric acid-d3	Endogenous Metabolite	Neurological Disease
1,7-Dimethyluric acid-d₃ is the deuterium labeled 1,7-Dimethyluric acid. 1,7-Dimethyluric acid is the metabolite of caffeine[1].

HY-119581

MBED 9-Methyl-7-bromoeudistomin D	Others	Neurological Disease
MBED (9-Methyl-7-bromoeudistomin D) is a RyR agonist. MBED is a high-affinity caffeine-like probe, helps identify the caffeine-binding site in RyRs .

HY-W016498

Paraxanthine 2 Publications Verification	Drug Metabolite Endogenous Metabolite	Neurological Disease
Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-W008449S

1-Methylxanthine-13C,d3	Endogenous Metabolite	Cancer
1-Methylxanthine- ¹³C,d₃ is the ¹³C- and deuterium labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

HY-W008449S1

1-Methylxanthine-13C4,15N3	Endogenous Metabolite	Cancer
1-Methylxanthine- ¹³C₄, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

HY-W016498S

Paraxanthine-d6	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Paraxanthine-d₆ is the deuterium labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-W016498R

Paraxanthine (Standard)	Drug Metabolite Endogenous Metabolite	Neurological Disease
Paraxanthine (Standard) is the analytical standard of Paraxanthine. This product is intended for research and analytical applications. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-W016498S1

Paraxanthine-13C4,15N3	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Paraxanthine- ¹³C₄, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-119575

Tetramethyluric acid 1,3,7,9-Tetramethyluric acid; Theacrine	Biochemical Assay Reagents	Others
Tetramethyluric acid (1,3,7,9-Tetramethyluric acid; Theacrine), also known as tetramethyluric acid or theophylline, is a purine alkaloid with a structure similar to caffeine. Tetramethyluric acid is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences .

HY-124257

(R)-Citronellol D-Citronellol; (R)-(+)-β-Citronellol	Endogenous Metabolite	Inflammation/Immunology
(R)-Citronellol (D-Citronellol) is an alcoholic monoterpene found in geranium essential oil. (R)-Citronellol inhibits degranulation of mast cells and does not affect caffeine bitterness perception. (R)-Citronellol can be used in decorative cosmetics, toiletries as well as in non-cosmetic products .

HY-138973A

Neramexane mesylate	iGluR nAChR	Neurological Disease
Neramexane mesylate is an α9α10 cholinergic nicotinic receptors and N-methyl-D-aspartate receptors(NMDA) antagonist. Neramexane mesylate can improve moderate to severe tinnitus, and also shows neuroprotective effects .

HY-P1604

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ⁺Caffeine, and Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation .

HY-P1604A

ATX-II TFA	Sodium Channel	Inflammation/Immunology
ATX-II TFA is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II TFA causes delayed inactivation of the Na ⁺Caffeine, and Ryanodine (HY-103306). ATX-II TFA also induces pulmonary vein arrhythmogenesis and atrial fibrillation .

HY-W017389R

Xanthine (Standard)	Endogenous Metabolite	Inflammation/Immunology
Xanthine (Standard) is the analytical standard of Xanthine. This product is intended for research and analytical applications. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation . In Vitro: A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme.

Cat. No.	Product Name	Type

HY-D2264

Caffeine orange	Fluorescent Dyes/Probes
Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

Caffeine orange

Fluorescent Dyes/Probes

Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

Cat. No.	Product Name	Type

HY-119575

Tetramethyluric acid 1,3,7,9-Tetramethyluric acid; Theacrine	Biochemical Assay Reagents
Tetramethyluric acid (1,3,7,9-Tetramethyluric acid; Theacrine), also known as tetramethyluric acid or theophylline, is a purine alkaloid with a structure similar to caffeine. Tetramethyluric acid is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences .

Cat. No.	Product Name	Target	Research Area

HY-P1604A

ATX-II TFA	Sodium Channel	Inflammation/Immunology
ATX-II TFA is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II TFA causes delayed inactivation of the Na ⁺Caffeine, and Ryanodine (HY-103306). ATX-II TFA also induces pulmonary vein arrhythmogenesis and atrial fibrillation .

HY-P1604

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ⁺Caffeine, and Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W016415

7-Methyluric acid	Structural Classification Alkaloids Other Alkaloids Source classification Endogenous metabolite	Biochemical Assay Reagents Endogenous Metabolite
7-Methyluric acid is a metabolite of caffeine. 7-Methyluric acid can be detected in urine .

HY-113327

1,3,7-Trimethyluric acid	Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort .

HY-W008449

1-Methylxanthine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Drug Metabolite Endogenous Metabolite
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) . 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-W016498

Paraxanthine 2 Publications Verification	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Drug Metabolite Endogenous Metabolite
Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-124257

(R)-Citronellol D-Citronellol; (R)-(+)-β-Citronellol	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Source classification Pelargonium hortorum Plants Endogenous metabolite Geraniaceae Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
(R)-Citronellol (D-Citronellol) is an alcoholic monoterpene found in geranium essential oil. (R)-Citronellol inhibits degranulation of mast cells and does not affect caffeine bitterness perception. (R)-Citronellol can be used in decorative cosmetics, toiletries as well as in non-cosmetic products .

HY-126061

1,7-Dimethyluric acid	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Neurological Disease Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,7-Dimethyluric acid is the metabolite of caffeine .

HY-N7564

Methylliberine	Structural Classification Alkaloids Other Alkaloids Source classification Rubiaceae Plants Coffea arabica L.	Others
Methylliberine is a purine alkaloid metabolite of caffeine with oral activity .

HY-W008449R

1-Methylxanthine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Drug Metabolite Endogenous Metabolite
1-Methylxanthine (Standard) is the analytical standard of 1-Methylxanthine. This product is intended for research and analytical applications. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) . 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-W016498R

Paraxanthine (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Drug Metabolite Endogenous Metabolite
Paraxanthine (Standard) is the analytical standard of Paraxanthine. This product is intended for research and analytical applications. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-W017389R

Xanthine (Standard)	Structural Classification Natural Products Microorganisms Source classification Disease markers Endocrine diseases Nervous System Disorder Camellia sinensis (L.) O. Ktze. Plants Endogenous metabolite Theaceae	Endogenous Metabolite
Xanthine (Standard) is the analytical standard of Xanthine. This product is intended for research and analytical applications. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation . In Vitro: A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme.

Cat. No.	Product Name	Chemical Structure

HY-W016498S

Paraxanthine-d6
Paraxanthine-d₆ is the deuterium labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-W016498S1

Paraxanthine-13C4,15N3
Paraxanthine- ¹³C₄, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

HY-W008449S2

1-Methylxanthine-d3
1-Methylxanthine-d₃ is deuterated labeled 1-Methylxanthine (HY-W008449). 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) . 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-126061S

1,7-Dimethyluric acid-d3
1,7-Dimethyluric acid-d₃ is the deuterium labeled 1,7-Dimethyluric acid. 1,7-Dimethyluric acid is the metabolite of caffeine[1].

HY-W008449S

1-Methylxanthine-13C,d3
1-Methylxanthine- ¹³C,d₃ is the ¹³C- and deuterium labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

HY-W008449S1

1-Methylxanthine-13C4,15N3
1-Methylxanthine- ¹³C₄, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

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caffeine

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products