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Results for "

chlorine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (3) DNA/RNA Synthesis (1) Estrogen Receptor/ERR (1) Fluorescent Dye (1) Phosphodiesterase (PDE) (1) Proteasome (1) Reactive Oxygen Species (1) Transthyretin (TTR) (1)
By Research Areas:	Cancer (4) Infection (1) Metabolic Disease (1) Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137905

Pomalidomide-amido-C5-PEG2-C6-chlorine	Others	Cancer
Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivant of Pomalidomide (HY-10984) .

HY-D0947

Azure A chloride	Fluorescent Dye	Others
Azure A (chloride) is a phenothiazine dye. Azure A (chlorine) is formed by oxidation of methylene blue and has strong metachromatic. Azure A (chlorine) can be used for the study of stains and redox media for electrochemical biosensing .

HY-128431

Arochlor 1254	Reactive Oxygen Species	Neurological Disease Metabolic Disease
Arochlor 1254 is a polychlorinated biphenyl (PCB) mixture with biphenyl and 54% chlorine. Aroclor 1254 reduced cell viability and induced overproduction of intracellular reactive oxygen species in a dose-dependent manner. Arochlor 1254 exposure reduces calcium homeostasis, osteoblast differentiation and bone formation .

HY-133629

1,1,1,3-Tetrachloroacetone	Others	Others
1,1,1,3-Tetrachloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133625

1,1-Dibromo-3-chloroacetone	Others	Others
1,1-Dibromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133627

1,3-Dibromo-1,3-dichloroacetone	Others	Others
1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133628

1,1,3-Tribromo-3-chloroacetone	Others	Others
1,1,3-Tribromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133626

1,1-Dibromo-3,3-dichloroacetone	Others	Others
1,1-Dibromo-3,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133658

Chloroiodoacetic acid	Others	Others
Chloroiodoacetic acid exists in the water disinfected with chlorine/hypochlorite .

HY-Y0537K

Potassium chloride, ACS, 99.0%	Biochemical Assay Reagents	Others
Potassium chloride, ACS, 99.0% is a metal halide salt composed of potassium and chlorine .

HY-116772

Cyanox CY 1790 Irganox 1790	Others	Others
Cyanox CY 1790 (Irganox 1790) is an antioxidant with chlorine dioxide resistance .

HY-133602

Tetrachloroguaiacol	Others	Others
Tetrachloroguaiacol is the major chlorinated phenol produced during chlorine bleaching of wood pulp .

HY-133603

4,5-Dichloroveratrole	Others	Others
4,5-Dichloroveratrole is a chlorinated product formed by reaction of Veratryl alcohol (VE; HY-107858) with chlorine dioxide solution .

HY-134404

6-Cl-PuTP	Biochemical Assay Reagents	Infection
6-Cl-PuTP is an ATP analog with active chlorine functionality. 6-Cl-PuTP can be used in viral disease related research .

HY-133646

Bromochloroacetonitrile	DNA/RNA Synthesis	Others
Bromochloroacetonitrile is a by-product of the chlorine disinfection of water containing natural organic material. Bromochloroacetonitrile possesses direct acting mutagenic activity and is capable of inducing DNA strand breakage .

HY-127074

Chlorendic acid HET acid	Biochemical Assay Reagents	Others
Chlorendic acid (HET acid) can be used as a diacid component for the synthesis of oligoesters with potential flame retardant properties with aliphatic diols. Degradation by chlorine radicals may be responsible for the flame retardancy of HET acid-based oligoesters .

HY-134406

6-Cl-cPuMP sodium	Phosphodiesterase (PDE)	Neurological Disease
6-Cl-cPuMP (sodium) is a cAMP analog with active chlorine function. 6-Cl-cPuMP (sodium) has good membrane permeability and phosphodiesterase (PDE) stability. 6-Cl-cPuMP (sodium) can be used for nervous system research .

HY-119417A

Chloramben sodium	Others	Others
Chloramben sodium is a herbicide with anti-growth activity against plants. Chloramben sodium can be effectively removed by photo-Fenton reaction under natural pH conditions, showing good degradation performance. The removal rate of chloramben sodium is consistent with different electrodes, mainly due to the oxidation mediated by the hydroxyl ions formed in the Fenton reaction. Chloramben sodium is almost completely mineralized using IrO2-based electrodes at high current density, indicating that it can be effectively degraded under light. Chloramben sodium leads to the formation of persistent chlorine derivatives in chlorine-containing environments, so the removal rate and mineralization rate are slightly reduced. Chloramben sodium can form intermediates with a variety of aromatic compounds and organic acids, reflecting the complexity of its transformation in the environment .

HY-143439

LX-039	Estrogen Receptor/ERR	Cancer
LX-039 is a highly potent, selective and orally active estrogen receptor degrader with EC₅₀ value of 2.29 nM. LX-039 has indole C-3 chlorine atom. LX-039 exhibits excellent mouse pharmacokinetics, low clearance, high C_max and oral exposure. LX-039 has anti-tumor activity .

HY-161505

Transthyretin-IN-3	Transthyretin (TTR)	Others
Transthyretin-IN-3 (compound 6) is a designed benzofuran analogue. Transthyretin-IN-3 selectively binds to plasma transthyretin (TTR) to inhibit Amyloid aggregation (IC₅₀=5.0±0.2 μM). Transthyretin-IN-3 can bind to TTR's thyroxine binding site specifically by carrying chlorine substituents at specific locations in its structure. This binding can prevent TTR tetramers from dissociating into unstable monomers .

HY-76779

4-(Chloromethyl)-7-hydroxycoumarin	Others	Cancer
4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .

HY-163770

Anticancer agent 233	Proteasome	Cancer
Anticancer agent 233 (compound 5g) is a 3,5-bis(arylmethylene)-4-piperidinone derivative with anticancer activity, with GI₅₀ of 0.25 and 0.23 μM for cervical cancer (HeLa) and colon cancer (HCT116) cell lines, respectively. The chlorine atom on the aromatic ring of Anticancer agent 233 interacts well with the catalytic site of 20S proteasome, inhibiting the activity of 20S proteasome to exert its anticancer effect .

Cat. No.	Product Name	Type

HY-D0947

Azure A chloride	Dyes
Azure A (chloride) is a phenothiazine dye. Azure A (chlorine) is formed by oxidation of methylene blue and has strong metachromatic. Azure A (chlorine) can be used for the study of stains and redox media for electrochemical biosensing .

Potassium chloride, ACS, 99.0%	Buffer Reagents
Potassium chloride, ACS, 99.0% is a metal halide salt composed of potassium and chlorine .

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