2. Search Result
Search Result
Results for "

crystallization

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

4

Biochemical Assay Reagents

3

Inhibitory Antibodies

4

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2514
    α-Lactose

    α-D-Lactose

    		 Others Others
    α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .
    α-Lactose
  • HY-161716
    LH1753

    		Others Others
    LH1753 is an orally active L-cystine crystallization inhibitor with an EC50 of 29.5 nM. LH1753 can be used for Cystinuria research .
    LH1753
  • HY-161715
    LH708

    		Others Others
    LH708 is an orally active L-cystine crystallization inhibitor with an EC50 of 59.8 nM. LH708 can be used for Cystinuria research .
    LH708
  • HY-132929
    TCMDC-125431

    		Parasite Infection
    TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
    TCMDC-125431
  • HY-132930
    TCMDC-136230

    		Parasite Infection
    TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
    TCMDC-136230
  • HY-131591
    Digalacturonic acid

    		Endogenous Metabolite Others
    Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K .
    Digalacturonic acid
  • HY-135253
    GR122222X

    		Others Others
    GR122222X is a DNA gyrase B protein inhibitor related to the cyclothiidine structure, which allows the crystallization of this protein fragment for molecular replacement studies.
    GR122222X
  • HY-19158
    Org 13011

    		Others Others
    Org 13011 is a compound with central nervous system activity. Various crystalline forms can be obtained by different crystallization methods, and new crystalline forms can be discovered by high temperature analysis.
    Org 13011
  • HY-P99919
    Efmarodocokin alfa

    		Interleukin Related Infection
    Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia .
    Efmarodocokin alfa
  • HY-125830
    ITIC

    		Others Others
    ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes. ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 °C.
    ITIC
  • HY-132931
    TCMDC-125457

    		Parasite Infection
    TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
    TCMDC-125457
  • HY-116285S1
    1-O-n-Octyl-β-D-glucopyranoside-d17

    		Isotope-Labeled Compounds Others
    1-O-n-Octyl-β-D-glucopyranoside-d17 is the deuterium labeled n-Octyl β-D-glucopyranoside[1]. n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins[2][3].
    1-O-n-Octyl-β-D-glucopyranoside-d17
  • HY-P9976A
    Isatuximab (anti-CD38)
    1 Publications Verification

    		 CD38 Cancer
    Isatuximab (anti-CD38) is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38.Isatuximab induces tumor cell killing via fragment crystallizable (Fc)-dependent or Fc-independent mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC) .
    Isatuximab (anti-CD38)
  • HY-P99665
    Insulin efsitora alfa

    LY-3209590

    		 Insulin Receptor Metabolic Disease
    Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes .
    Insulin efsitora alfa
  • HY-W414390
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98%

    2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%

    		 Biochemical Assay Reagents Others
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98% (2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%) is a detergent that can be used for the purification and crystallization of membrane-bound proteins in their native structure. It can self-assemble into micelles and vesicles in aqueous solution and can be used for the study of biomembrane models.
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98%
  • HY-123622
    CYMAL-5, 98% (TLC)

    		Biochemical Assay Reagents Others
    CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .
    CYMAL-5, 98% (TLC)
  • HY-W250181
    Octyl thiomaltoside

    Octyl β-D-thiomaltopyranoside

    		 Biochemical Assay Reagents Others
    Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.
    Octyl thiomaltoside
  • HY-121120
    Isosulfazecin

    		Antibiotic Infection
    Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .
    Isosulfazecin
  • HY-117074
    BMS-247243

    		Others Infection
    BMS-247243 is a β-lactam antibiotic against methicillin-resistant Staphylococcus aureus. This section introduces its synthesis method and biological properties. A practical synthetic method was developed to exchange iodide ions with chloride ions to form 4-thiopyridinol 6b with C-3 side chain, thereby effectively synthesizing methyl ester 12b with C-7 side chain. The reaction of 14 with methylthiolate lithium salt was catalyzed by Bu4NCl to form methyl ester 12b in high yield. Reaction with thiolate dianion gave the corresponding Michael addition byproduct, resulting in a decrease in the quality of thermodynamic product 12b. The diester 17 was synthesized by acid chlorination acylation of 16 with 12b in a two-phase system, avoiding the troublesome deprotection work such as using DCC or EDAC. During the TFA reaction to remove the protecting group 17, the bis acid 20 was unexpectedly obtained. The bis acid 19 reacted with 4-thiopyridinol 6b to form BMS-247243 in moderate yield. Alternatively, efficient coupling of diester 17 with 4-thiopyridinol 6b afforded crystalline diester 21 with little contamination from isomer 22. Double deprotection of diester 21 followed by crystallization afforded the bis-zwitterion BMS-247243 in high yield.
    BMS-247243

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: