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LH1753 is an orally active L-cystine crystallization inhibitor with an EC50 of 29.5 nM. LH1753 can be used for Cystinuria research.

For research use only. We do not sell to patients.

LH1753 Chemical Structure

LH1753 Chemical Structure

CAS No. : 2650492-10-5

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Description

LH1753 is an orally active L-cystine crystallization inhibitor with an EC50 of 29.5 nM. LH1753 can be used for Cystinuria research[1].

In Vivo

LH1753 (150 μmol/kg, i.g., QD for 8 weeks) inhibits the L-cystine stone formation and has no effect on the growth of Slc3a1-knockout mouse model of cystinuria[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

630.57

Formula

C22H44Cl4N6O2S2

CAS No.
SMILES

O=C([C@@H](N)CSSC[C@H](N)C(N1CCC2(NCCC2)CC1)=O)N3CCC4(NCCC4)CC3.Cl.Cl.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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LH1753 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
LH1753
Cat. No.:
HY-161716
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