2. Natural Products
  3. Saccharides

Saccharides

Saccharides are the most abundant class of organic compounds found in living organisms and a major source of metabolic energy, both for plants and for animals that depend on plants for food. They are represented by a common formula Cm(H2O)n hence, often called carbohydrates. Saccharides are mainly grouped into: monosaccharides, disaccharides, oligosaccharides, and polysaccharides. Saccharides perform numerous structural as well as biological roles in living organisms. Polysaccharides serves as the reservoir of energy (e.g. starch and glycogen) and as structural components. The 5-carbon monosaccharide ribose is an important component of coenzymes (e.g. ATP, FAD and NAD) and the backbone of the genetic molecule known as RNA. The related deoxyribose is a component of DNA. They actively participate in energy storage and transport, signaling, cell-cell communication, pathogenesis, immune response and modulation of protein and lipid function.

 

Saccharides (550):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-D1056
    Lipopolysaccharides, from E. coli O55:B5
    Lipopolysaccharides, from E. coli O55:B5 is an endotoxin extracted from E. coli O55:B5, consisting of an antigen-specific chain, A core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activates TLR-4 of immune cells. Lipopolysaccharides, from E. coli O55:B5 can induce the change of body temperature in rats with dose and serotype specificity. Lipopolysaccharides, from E. coli O55:B5 caused a heterogeneous and dose-independent increase in body temperature in rats.
    Lipopolysaccharides, from E. coli O55:B5
  • HY-13966
    2-Deoxy-D-glucose 154-17-6 99.93%
    2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
    2-Deoxy-D-glucose
  • HY-N0210
    D-Galactose 59-23-4 99.20%
    D-Galactose is a natural aldohexose and C-4 epimer of glucose.
    D-Galactose
  • HY-B0389
    D-Glucose 50-99-7 ≥98.0%
    D-Glucose is the naturally occurring form of glucose and the most abundant monosaccharide. D-Glucose is a critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic or abiotic stress response.
    D-Glucose
  • HY-101916
    Heparan Sulfate 9050-30-0
    Heparan sulfate, a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix.
    Heparan Sulfate
  • HY-128852
    N-Acetyl-D-galactosamine, 98% 14215-68-0 ≥98.0%
    N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets. N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin.
    N-Acetyl-D-galactosamine, 98%
  • HY-N12800
    Paeonicluside 448231-30-9
    Paeonicluside is a salicylic glycoside and can be isolated from Paeonia clusii.
    Paeonicluside
  • HY-N12821
    visamminol-3'-O-glucoside 2254096-98-3
    Visamminol-3'-O-glucoside (Compound 4) is a chromone glycoside, which is initially isolated from Saposhnikovia divaricata. Visamminol-3'-O-glucoside exhibits weak cytotoxicity against cancer cells PC-3, SK-OV-3 and H460, with IC50s of 93.91, >100 and >100 μM, respectively.
    visamminol-3'-O-glucoside
  • HY-B0633A
    Hyaluronic acid 9004-61-9
    Hyaluronic acid (corn fermented) is a biopolymer composed of repeating units of disaccharides with various applications.
    Hyaluronic acid
  • HY-B0089
    Acarbose 56180-94-0 99.97%
    Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin.
    Acarbose
  • HY-132179
    Fucoidan 9072-19-9 98.15%
    Fucoidan, a biologically active polysaccharide, is an efficient inhibitor of α-amylase and α-glucosidase. Anticoagulant, antitumor, antioxidant and antisteatotic activities.
    Fucoidan
  • HY-I0400
    N-Acetylneuraminic acid 131-48-6 99.90%
    N-Acetylneuraminic acid (NANA; Lactaminic acid), a nonphenolic structure, is the predominant form of sialic from Collocalia esculenta. N-Acetylneuraminic acid plays a biological role in myocardial injury, melanoma and viral or bacterial infection. N-Acetylneuraminic acid inhibits melanogenesis by reducing tyrosinase activity and triggers myocardial injury in vitro and in vivo by activation of the Rho/Rho-associated signaling pathway through binding to RhoA and Cdc42. N-Acetylneuraminic acid may prevent high fat diet (HFD)-induced inflammation and oxidative stress, thereby prevents hyperlipidemia-associated inflammation and oxidative stress. N-Acetylneuraminic acid is promising for research in the field of melanoma, coronary artery, obesity-related diseases and hyperlipidemia.
    N-Acetylneuraminic acid
  • HY-B0400
    D-Sorbitol 50-70-4 99.95%
    D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement.
    D-Sorbitol
  • HY-B1125
    Glucosamine 3416-24-8 ≥98.0%
    Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
    Glucosamine
  • HY-N1132
    D-(+)-Trehalose 99-20-7 99.94%
    D-(+)-Trehalose,which is widespread, can be used as a food ingredient and pharmaceutical excipient.
    D-(+)-Trehalose
  • HY-B0633
    Hyaluronic acid sodium 9067-32-7 ≥98.0%
    Hyaluronic acid sodium (Sodium hyaluronate) is a biopolymer composed of repeating units of disaccharides with various applications.
    Hyaluronic acid sodium
  • HY-42682
    D(+)-Galactosamine hydrochloride 1772-03-8 ≥98.0%
    D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure.
    D(+)-Galactosamine hydrochloride
  • HY-N0379
    D-Mannose 3458-28-4 ≥98.0%
    D-Mannose is a C-2 superpolymer of glucose that occurs naturally in many plants and fruits. D-Mannose has anti-inflammatory and antitumor activity. D-Mannose plays an important role in immune regulation.
    D-Mannose
  • HY-B2162
    Chondroitin sulfate 9007-28-7 98.60%
    Chondroitin sulfate, one of five classes of glycosaminoglycans, has been widely used in the treatment of osteoarthritis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS and MMPs.
    Chondroitin sulfate
  • HY-119109
    Laminaran 9008-22-4 ≥98.0%
    Laminaran is an β-1-3-glucan and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities. Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds. Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy.
    Laminaran