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Results for "

diacylglycerol acyltransferase-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (8) Biochemical Assay Reagents (1)
By Research Areas:	Metabolic Disease (8)

Inhibitors & Agonists

Biochemical Assay Reagents

Antibodies

Targets Recommended: Acyltransferase DGK DAGL

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16278

Pradigastat 2 Publications Verification LCQ-908	Acyltransferase	Metabolic Disease
Pradigastat (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat has anti-obesity and anti-diabetic effects .

HY-15197

ABT-046	Acyltransferase	Metabolic Disease
ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC₅₀s of both 8 nM against human and mouse DGAT-1 .

HY-10038

A 922500 Maximum Cited Publications 15 Publications Verification DGAT-1 Inhibitor 4a	Acyltransferase	Metabolic Disease
A 922500 (DGAT-1 Inhibitor 4a) is a potent, selective, and orally bioavailable diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC₅₀s of 9 and 22 nM against human and mouse DGAT-1, respectively.

HY-15497

AZD7687 1 Publications Verification	Acyltransferase	Metabolic Disease
AZD7687 is a potent, selective, reversible and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor with an IC₅₀ of 80 nM for human DGAT1. AZD7687 can be used for type 2 diabetes mellitus and obesity research .

HY-141572

1,2-Dioleoyl-sn-glycerol sn-1,2-Dioleoylglycerol	Biochemical Assay Reagents	Others
ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6.

HY-32219

T863 5+ Cited Publications	Acyltransferase	Metabolic Disease
T863 is an orally active, selective and potent DGAT1 (acyl-CoA:diacylglycerol acyltransferase 1) inhibitor with an IC₅₀ of 15 nM. T863 has no inhibitory activity against human MGAT3, human DGAT2, or human MGAT2. T863 interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells .

HY-136707

DGAT-1 inhibitor 3	Acyltransferase	Metabolic Disease
DGAT-1 inhibitor 3 (compound 10) is a potent DGAT-1 inhibitor with an IC₅₀ value of 0.038 µM. DGAT-1 inhibitor 3 has the potential for the research of obesity and diabetes .

HY-111417

GSK2973980A	Acyltransferase	Metabolic Disease
GSK2973980A is a potent and selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor with an IC₅₀ of 3 nM.

HY-16278A

Pradigastat sodium LCQ 908 sodium	Acyltransferase	Metabolic Disease
Pradigastat sodium (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat sodium has anti-obesity and anti-diabetic effects .

Cat. No.	Product Name	Type

HY-141572

1,2-Dioleoyl-sn-glycerol sn-1,2-Dioleoylglycerol	Drug Delivery
ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6.

1,2-Dioleoyl-sn-glycerol

sn-1,2-Dioleoylglycerol

Drug Delivery

ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81246

	DGAT1 Antibody ACAT related gene product 1; ACAT-related gene product 1; Acyl coenzyme A:cholesterol acyltransferase related gene 1; Acyl-CoA retinol O-fatty-acyltransferase; Acyl-CoA:diacylglycerol acyltransferase; ARAT; ARGP1; C75990; D15Ertd23e; Dgat; DGAT1; DGAT1_HUMAN; diacylglycerol O acyltransferase 1; diacylglycerol O-acyltransferase 1; Diglyceride acyltransferase; EC 2.3.1.20; hCG_24006; MGC139064; Retinol O fatty acyltransferase.	WB, IHC-P, IP	Human
	DGAT1 Antibody is a rabbit-derived non-conjugated IgG antibody, targeting DGAT1, with a predicted molecular weight of 55 kDa (observed band size: 55 kDa). DGAT1 Antibody can be used for WB,IHC-P,IP experiments in human backgrounds.

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