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Results for "

hCE1

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Natural
Products

1

Recombinant Proteins

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106409
    Tefinostat
    1 Publications Verification

    CHR-2845

    		 HDAC Apoptosis Cancer
    Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias [1].
    Tefinostat
  • HY-N1377
    Nevadensin

    		Carboxylesterase Bacterial Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1 (hCE1) with an IC50 of 2.64 μM. Nevadensin has a variety of pharmacological effects such as anti-mycobacterium tuberculosis activities, antitussive, anti-inflammatory and anti-hypertensive [1] .
    Nevadensin
  • HY-144809
    Pancreatic lipase/Carboxylesterase 1-IN-1

    		Carboxylesterase Metabolic Disease
    Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A) with IC50 values of 2.13 µM and 0.055  µM against PL and hCES1A [1].
    Pancreatic lipase/Carboxylesterase 1-IN-1
  • HY-23148
    1-Methylisatin

    N-Methylisatin

    		 Carboxylesterase Others
    1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor, with Kis of 38.2 and 5.38 μM for hiCE and hCE1, respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo [1] .
    1-Methylisatin
  • HY-N1377R
    Nevadensin (Standard)

    		Carboxylesterase Bacterial Infection Metabolic Disease Inflammation/Immunology
    Nevadensin (Standard) is the analytical standard of Nevadensin. This product is intended for research and analytical applications. Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1 (hCE1) with an IC50 of 2.64 μM. Nevadensin has a variety of pharmacological effects such as anti-mycobacterium tuberculosis activities, antitussive, anti-inflammatory and anti-hypertensive [1] .
    Nevadensin (Standard)

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