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porcine pancreatic elastase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Elastase (4) Fluorescent Dye (2) Parasite (1) Ser/Thr Protease (1)
By Research Areas:	Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (2)

7

Inhibitors & Agonists

2

Fluorescent Dye

4

Peptides

Targets Recommended: Elastase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

MeOSuc-AAPV-AMC	Fluorescent Dye	Others
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm) .

ZD-0892	Elastase	Cardiovascular Disease
ZD-0892 is a selective and potent inhibitor of a neutrophil elastase with K_is of 6.7 and 200 nM for human neutrophil elastase and porcine pancreatic elastase, respectively.

MeOSuc-Ala-Ala-Pro-Val-pNA	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

FK706	Elastase	Inflammation/Immunology
FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC₅₀ of 83 nM and a K_i of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and **porcine pancreatic elastase with IC₅₀*s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic* trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect .

Midesteine MR 889	Ser/Thr Protease	Inflammation/Immunology
Midesteine (MR 889) is a proteinase inhibitor that can inhibit porcine pancreatic elastase, human neutrophil elastase and bovine chymotrypsin. Midesteine has the potential for chronic obstructive pulmonary disease (COPD) and chronic bronchitis research .

Suc-AAP-Abu-pNA Colorimetric elastase Substrate	Elastase	Others
Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for **pancreatic elastase** (K_m = 100 μM; K_cat/K_m = 35,300 s ^-1 M ^-1 for rat pancreatic elastase; K_m = 30 μM; K_cat/K_m = 351,000 s ^-1 M ^-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration .

JCP174	Elastase Parasite	Infection
JCP174 is an inhibitor of palmitoyl protein thioesterase-1 (TgPPT1), a depalmitoylase in the parasite T. gondii . JCP174 is also an inhibitor of porcine pancreatic elastase and human leukocyte elastase .

Cat. No.	Product Name	Target	Research Area

MeOSuc-AAPV-AMC	Fluorescent Dye	Others
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm) .

MeOSuc-Ala-Ala-Pro-Val-pNA	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

Suc-AAA-pNA	Peptides	Others
Suc-AAA-pNA?is the substrate of analysis of the reversible inhibition of porcine pancreatic elastase (PPE) .

Suc-AAP-Abu-pNA Colorimetric elastase Substrate	Elastase	Others
Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for **pancreatic elastase** (K_m = 100 μM; K_cat/K_m = 35,300 s ^-1 M ^-1 for rat pancreatic elastase; K_m = 30 μM; K_cat/K_m = 351,000 s ^-1 M ^-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration .

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