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psoralen

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By Targets:	Apoptosis (6) Autophagy (2) Bacterial (1) Biochemical Assay Reagents (1) Carboxylesterase (2) Cytochrome P450 (2) DNA Alkylator/Crosslinker (2) HIV (2) Influenza Virus (2) p38 MAPK (2) Potassium Channel (2) UGT (2) Virus Protease (2)
By Research Areas:	Cancer (11) Infection (3) Inflammation/Immunology (10) Metabolic Disease (3) Neurological Disease (1)
Click Chemistry:	Azide (1)

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Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0053

*Psoralen* 3 Publications Verification Ficusin	Apoptosis HIV Influenza Virus	Cancer
Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al .

HY-N5110

Marmesinin (-)-Marmesinin; Ammijin	Others	Neurological Disease
Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity .

HY-10015

PAP-1 5+ Cited Publications 5-(4-Phenoxybutoxy)psoralen	Potassium Channel	Inflammation/Immunology
PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC₅₀=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC₅₀=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects .

HY-150014

AMT-NHS	Others	Others
AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .

HY-N0053R

Psoralen (Standard)	Apoptosis HIV Influenza Virus	Cancer
Psoralen (Standard) is the analytical standard of Psoralen. This product is intended for research and analytical applications. Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al .

HY-N9538

8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen	Others	Others
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin that can be found in Heracleum pyrenaicum Lam.

HY-N9288

8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen	Others	Others
8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Psoralea corylifolia L. .

HY-N8626

8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen	Others	Others
8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Phebalium tuberculosum ssp. megaphyllum .

HY-151118

HER2-IN-11	Apoptosis	Cancer
HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis .

HY-151116

HER2-IN-10	Apoptosis	Cancer
HER2-IN-10 is a psoralen derivative. HER2-IN-10 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-10 induces apoptosis .

HY-108583

Psora-4 5-(4-Phenylbutoxy)psoralen	Potassium Channel	Inflammation/Immunology
Psora-4 is a potent and selective inhibitor of K_v1.3 (voltage-gated potassium channels) with an EC₅₀ of 3 nM . Psora-4 has immunosuppressive activity and inhibits proliferation of human and rat myelin-specific effector memory T cells in vitro .

HY-107004A

Amotosalen hydrochloride 1 Publications Verification S-59	Others	Inflammation/Immunology
Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens .

HY-107004

Amotosalen S-59 free base	Others	Inflammation/Immunology
Amotosalen (S-59 (free base)) is a light-activated, DNA and RNA-crosslinking psoralen compound, which is used to neutralise pathogens .

HY-30151

Methoxsalen Maximum Cited Publications 12 Publications Verification 8-Methoxypsoralen; Xanthotoxin; 8-MOP	Cytochrome P450	Inflammation/Immunology Cancer
Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

HY-30151R

Methoxsalen (Standard)	Cytochrome P450	Inflammation/Immunology Cancer
Methoxsalen (Standard) is the analytical standard of Methoxsalen. This product is intended for research and analytical applications. Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

HY-N7504

Isopsoralenoside	Bacterial	Infection Metabolic Disease Cancer
Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .

HY-N0763

Angelicin 5+ Cited Publications Isopsoralen	Apoptosis Virus Protease	Cancer
Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC50: 49.56 μM; inhibits MHV-68, IC50: 5.39 μg/ml (28.95 μM).

HY-B1157

Trioxsalen 2 Publications Verification Trisoralen; Trioxysalen; TMP	DNA Alkylator/Crosslinker	Inflammation/Immunology
Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation .

HY-137265

Aminomethyltrioxsalen hydrochloride	Biochemical Assay Reagents	Others
Aminomethyltrioxsalen hydrochloride is a derivative of Psoralen (HY-N0053). Aminomethyltrioxsalen hydrochloride penetrate intact cells and form interstrand crosslinks between pyrimidine residues of nucleic acid helices upon irradiation with ultraviolet light as a bifunctional nucleic acid intercalating agent, which can be used as a probe for double-stranded regions in heterogeneous nuclear RNA (hnRNA) to detect the secondary structure of hnRNA .

HY-N0763R

Angelicin (Standard)	Apoptosis Virus Protease	Cancer
Angelicin (Standard) is the analytical standard of Angelicin. This product is intended for research and analytical applications. Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC₅₀: 49.56 μM; inhibits MHV-68, IC₅₀: 5.39 μg/ml (28.95 μM).

HY-B1157R

Trioxsalen (Standard)	DNA Alkylator/Crosslinker	Inflammation/Immunology
Trioxsalen (Standard) is the analytical standard of Trioxsalen. This product is intended for research and analytical applications. Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation .

HY-N0235

Bakuchiol 2 Publications Verification (S)-(+)-Bakuchiol	Carboxylesterase p38 MAPK Autophagy UGT	Infection Metabolic Disease Inflammation/Immunology Cancer
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

HY-N0235R

Bakuchiol (Standard)	Carboxylesterase p38 MAPK Autophagy UGT	Infection Metabolic Disease Inflammation/Immunology Cancer
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

*Psoralen* 3 Publications Verification Ficusin	Structural Classification Classification of Application Fields Leguminosae Source classification Coumarins Phenylpropanoids Psoralea corylifolia L. Plants Disease Research Fields Cancer	Apoptosis HIV Influenza Virus
Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al .

Marmesinin (-)-Marmesinin; Ammijin	Pseudognaphalium affine (D. Don) Anderberg Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity .

Methoxsalen Maximum Cited Publications 12 Publications Verification 8-Methoxypsoralen; Xanthotoxin; 8-MOP	Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields Cancer	Cytochrome P450
Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

Isopsoralenoside	Infection Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Source classification Metabolic Disease Psoralea corylifolia L. Plants Disease Research Fields	Bacterial
Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .

Angelicin 5+ Cited Publications Isopsoralen	Structural Classification Classification of Application Fields Leguminosae Source classification Coumarins Phenylpropanoids Psoralea corylifolia L. Plants Disease Research Fields Cancer	Apoptosis Virus Protease
Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC50: 49.56 μM; inhibits MHV-68, IC50: 5.39 μg/ml (28.95 μM).

Psoralen (Standard)	Structural Classification Leguminosae Source classification Coumarins Phenylpropanoids Psoralea corylifolia L. Plants	Apoptosis HIV Influenza Virus
Psoralen (Standard) is the analytical standard of Psoralen. This product is intended for research and analytical applications. Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al .

8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen	other families Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields	Others
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin that can be found in Heracleum pyrenaicum Lam.

8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen	Structural Classification Leguminosae Source classification Coumarins Phenylpropanoids Psoralea corylifolia L. Plants	Others
8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Psoralea corylifolia L. .

8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen	Structural Classification Phebalium tuberculosum (F.Muell.) Benth. Source classification Rutaceae Coumarins Phenylpropanoids Plants	Others
8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Phebalium tuberculosum ssp. megaphyllum .

Methoxsalen (Standard)	Structural Classification other families Source classification Coumarins Phenylpropanoids Plants	Cytochrome P450
Methoxsalen (Standard) is the analytical standard of Methoxsalen. This product is intended for research and analytical applications. Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

Angelicin (Standard)	Structural Classification Leguminosae Source classification Coumarins Phenylpropanoids Psoralea corylifolia L. Plants	Apoptosis Virus Protease
Angelicin (Standard) is the analytical standard of Angelicin. This product is intended for research and analytical applications. Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC₅₀: 49.56 μM; inhibits MHV-68, IC₅₀: 5.39 μg/ml (28.95 μM).

Bakuchiol 2 Publications Verification (S)-(+)-Bakuchiol	Structural Classification Monophenols Classification of Application Fields Leguminosae Source classification Phenols Psoralea corylifolia L. Plants Disease Research Fields Cancer	Carboxylesterase p38 MAPK Autophagy UGT
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

Bakuchiol (Standard)	Structural Classification Monophenols Leguminosae Source classification Phenols Psoralea corylifolia L. Plants	Carboxylesterase p38 MAPK Autophagy UGT
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

Cat. No.	Product Name		Classification

HY-163213

Psoralen-triethylene glycol azide		Azide
Psoralen-triepthylene glycol azide is a compound used to probe the structure and conformation of RNA in living cells, using matching RNA crosslinking and deep sequencing or comradery methods .

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psoralen

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