Search Result
Results for "
solubilization
" in MedChemExpress (MCE) Product Catalog:
37
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y0537C
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Potassium chloride, suitable for the extraction and solubilization of proteins
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Biochemical Assay Reagents
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Others
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Potassium chloride, ≥99.99% trace metals basis is a biochemical assay reagent suitable for protein extraction and solubilization.
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- HY-44157
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Biochemical Assay Reagents
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Neurological Disease
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ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain .
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- HY-D1005F
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PEG-PPG-PEG, 2500(Average Mn)
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Biochemical Assay Reagents
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Others
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Poloxamer 182 (L62) can be used as an excipient, such as Emulsifier, solubilizer, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-135737
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Others
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Others
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Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .
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- HY-138193
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LMNG
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Others
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Others
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Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes .
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- HY-136962
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Amidosulfobetaine-14
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Biochemical Assay Reagents
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Others
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ASB-14 (Amidosulfobetaine-14) is a zwitterionic amidosulfobetaine surfactant with membrane protein solubilizing. ASB-14 can be used for the preparative extraction and solubilization of proteins .
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- HY-154637
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Biochemical Assay Reagents
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Others
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Sucrose Stearate can be used as an excipient, such as Surfactants, emulsifiers, solubilizers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-154639
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Biochemical Assay Reagents
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Others
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Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-19037
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Adrenergic Receptor
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Neurological Disease
Metabolic Disease
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SM-2470 is a potent α1-adrenoceptor antagonist, has sympathetic nerve activity in anesthetized rats . SM-2470 is an antihypertensive agent. SM-2470 exhibits hypocholesterolaemic effect by the inhibition of cholesterol absorption related to the reduction of cholesterol solubilization .
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- HY-W097331
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Others
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Others
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Salicylamide-O-acetic acid is a theophylline solubilizer .
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- HY-Y0537B
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Biochemical Assay Reagents
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Cancer
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Potassium chloride, for molecular biology is a potassium chloride that can be used at the molecular level for protein extraction and solubilization.
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- HY-W019895
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Others
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Others
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Tetradecylphosphocholine is a zwitterionic surfactant that can be used as a detergent for membrane protein solubilization .
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- HY-W127401
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- HY-158724
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Others
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Others
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Calxgluk (compound 18 in page 22) is a calixarene detergent that can be used to solubilize membrane proteins .
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- HY-166519
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α‐HPCD (MW 1180)
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Biochemical Assay Reagents
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Others
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(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) is a cyclic oligosaccharide derivative that acts as a solubilizer in various experiments.
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- HY-W250172
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Biochemical Assay Reagents
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Others
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Triton X-405 is a nonionic surfactant commonly used in a variety of industrial and research applications. Triton X-405 belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in emulsions, detergents and solubilizers. Triton X-405 is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. It is also used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Additionally, Triton X-405 is used in the production of microemulsions, salves and lotions due to its emulsifying and solubilizing properties. However, it can be toxic if ingested or inhaled, so proper handling and safety precautions are required.
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- HY-Y0873P
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Polyethylene glycol 10000
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Biochemical Assay Reagents
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Others
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PEG10000 (Polyethylene glycol 10000) can be used as a solubilizer. PEG10000 is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-B1620D
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PVP K25; Polyvidone K25; Povidone K25
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Biochemical Assay Reagents
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Others
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Polyvinylpyrrolidone K25 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K25 can be used as stabilizer, emulsifier, suspension agent, solubilizer, protective colloid and complexing agent .
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- HY-B1620E
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PVP K60; Polyvidone K60; Povidone K60
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Biochemical Assay Reagents
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Others
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Polyvinylpyrrolidone K60 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K60 can be used as stabilizer, emulsifier, suspension agent, solubilizer, protective colloid and complexing agent .
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- HY-158083
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Biochemical Assay Reagents
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Others
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Polymethacrylate Copolymer forms nanodiscs spontaneously by fragmentation or solubilization of the lipid bilayers.Polymethacrylate Copolymer is used in designing of nanodisc-forming polymer to mimic the amphiphilic nature of proteins and peptides .
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- HY-15435
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CHAPS
2 Publications Verification
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Others
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Others
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CHAPS, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution .
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- HY-15435A
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Biochemical Assay Reagents
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Others
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CHAPS hydrate, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution .
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- HY-Y0873Q
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Polyethylene glycol 20000
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Biochemical Assay Reagents
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Others
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PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria .
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- HY-W250178
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Biochemical Assay Reagents
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Others
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Octaethylene glycol monodecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monodecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monodecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.
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- HY-W250195
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Biochemical Assay Reagents
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Others
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Hexaethylene glycol monotetradecyl ether is a kind of nonionic surfactant with hydrophilic head and lipophilic tail. It belongs to the class of polyethylene glycol (PEG) ethers and is widely used in different industrial and research applications. Due to its unique properties, Hexaethylene glycol monotetradecyl ether is commonly used in lotions, detergents and solubilizers. It is particularly useful in the study of membrane proteins and can be used to stabilize and solubilize proteins for use in structural analysis techniques. Due to its moisturizing and emulsifying properties, Hexaethylene glycol monotetradecyl ether is also used in personal care and cosmetics.
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- HY-W250176
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Biochemical Assay Reagents
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Others
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Polyethylene glycol trimethylnonyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Polyethylene glycol trimethylnonyl ether is particularly useful in protein chemistry, where it is used to solubilize and stabilize proteins, such as membrane proteins, for structural analysis techniques. In addition, Polyethylene glycol trimethylnonyl ether has potential applications in drug delivery and other medical fields due to its ability to interact with and penetrate cell membranes.
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- HY-W040224
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Biochemical Assay Reagents
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Others
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Octyl β-D-thioglucopyranoside is a non-ionic detergent that can be used in the field of membrane biochemistry. Octyl β-D-thioglucopyranoside has the ability to solubilize E. coli membrane proteins .
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- HY-W099581
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SB3-14; DMAPS
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Biochemical Assay Reagents
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Others
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Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
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- HY-W250171
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Polyoxyethylene (10) cetyl ether
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Biochemical Assay Reagents
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Others
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Octaethylene glycol monohexadecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. Octaethylene glycol monohexadecyl ether belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail, suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monohexadecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monohexadecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.
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- HY-138941
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C12E8
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Influenza Virus
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Infection
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Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus .
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- HY-151787
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ADC Linker
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Others
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Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-N2334AS
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Chenodeoxycholylglycine-d7 (sodium); Sodium glycochenodeoxycholate-d7
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Endogenous Metabolite
Apoptosis
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Cancer
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Glycochenodeoxycholic acid-d7 (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].
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- HY-N2334S
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Chenodeoxycholylglycine-d4
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Isotope-Labeled Compounds
Endogenous Metabolite
Apoptosis
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Cancer
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Glycochenodeoxycholic acid-d4 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2].
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- HY-151786
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ADC Linker
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Others
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Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-16984
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Itk
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Inflammation/Immunology
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GNE-4997 is a potent and selective interleukin-2-inducible T-cell kinase (ITK) inhibitor with a Ki of 0.09 nM, and the correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity .
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- HY-W099581R
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Biochemical Assay Reagents
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Others
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Sulfobetaine-14 (Standard) is the analytical standard of Sulfobetaine-14. This product is intended for research and analytical applications. Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
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- HY-P5878
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Biochemical Assay Reagents
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Metabolic Disease
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RG33 Peptide is a diabetes inhibitor that significantly improves glucose clearance in insulin-resistant mice. RG33 Peptide effectively solubilizes lipid vesicles and promotes cholesterol efflux in cultured macrophages. RG33 Peptide is used in research into type 2 diabetes (T2D) .
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- HY-W440898
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Biochemical Assay Reagents
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Others
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DSPE-PEG-SH, MW 5000 is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide. Reagent grade, for research use only.
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- HY-126403
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PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated
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Biochemical Assay Reagents
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Others
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Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .
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- HY-W127627
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Biochemical Assay Reagents
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Others
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Tween 85 is a nonionic surfactant belonging to the class of ethoxylated sorbitan esters. It is used as an emulsifier and solubilizer in various industries such as pharmaceutical, cosmetic and food. Because of its ability to blend oily and water-based ingredients, Tween 85 is often used in the formulation of creams, lotions and ointments. In addition, it is used as a dispersant for pigments in the production of paints and coatings.
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- HY-134924
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Biochemical Assay Reagents
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Others
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Succinyl-β-cycloaltrin is a modified cyclodextrin with unique chemical properties that make it an effective solubilizer and stabilizer for various compounds, especially in the pharmaceutical industry. Succinyl-β-cycloaltrin has a hydrophobic interior and a hydrophilic exterior, enabling it to form stable clathrates with hydrophobic molecules such as drugs and nutrients. This increases their solubility and bioavailability, making them more effective for recreational or nutritional purposes.
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- HY-116285S1
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Isotope-Labeled Compounds
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Others
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1-O-n-Octyl-β-D-glucopyranoside-d17 is the deuterium labeled n-Octyl β-D-glucopyranoside[1]. n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins[2][3].
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- HY-Y1883A
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Biochemical Assay Reagents
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Infection
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Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant .
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- HY-101461
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Methyl-beta-cyclodextrin
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Biochemical Assay Reagents
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Cancer
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Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .
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- HY-W013076
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tetra(decyl)ammonium bromide
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Biochemical Assay Reagents
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Others
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Tetrakis(decyl)ammonium bromide is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrakis(decyl)ammonium bromide is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, cleansers and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, facilitating the movement of reactants between immiscible phases.
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- HY-E70013
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endo-1,3:1,4-β-D-Glucanase
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Endogenous Metabolite
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Metabolic Disease
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Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .
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- HY-160281
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Others
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Metabolic Disease
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CCD-2 is a conventional detergent and is readily degraded. CCD-2 can efficiently solubilize and stabilize diverse G protein-coupled receptors (GPCRs). CCD-2 is amenable to the β-barrel protein research. The chemical cleavage of CCD-2 is rapid, complete and biorthogonal and should facilitate a chemical methodology for in situ detergent replacement in diverse membrane proteins (MPs) studies .
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- HY-W099575
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Biochemical Assay Reagents
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Others
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3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.
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- HY-W440901
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Liposome
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Others
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DSPE-PEG-SPDP, MW 5000 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond. Reagent grade, for research use only.
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- HY-W142692
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Biochemical Assay Reagents
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Others
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Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration .
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- HY-137234
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2,6-Di-O-methyl-β-cyclodextrin
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Biochemical Assay Reagents
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Others
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DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
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- HY-W008974
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Biochemical Assay Reagents
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Others
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3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA.
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- HY-W250166
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Biochemical Assay Reagents
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Others
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Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.
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- HY-154630
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Biochemical Assay Reagents
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Others
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Polyoxypropylene stearyl ether can be used as an excipient, such as surfactant, softener, lubricating, wetting, plasticizing, solubilizing and dispersing properties. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-101530C
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PEG 100 stearate
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Biochemical Assay Reagents
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Others
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Polyoxyl 100 stearate can be used as an excipient, such as o/w emulsifiers, solubilizers, ointment and suppository bases. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-W250181
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Octyl β-D-thiomaltopyranoside
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Biochemical Assay Reagents
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Others
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Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.
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- HY-Y1883AR
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Biochemical Assay Reagents
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Infection
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Triton X-100 (Standard) is the analytical standard of Triton X-100. This product is intended for research and analytical applications. Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant .
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- HY-W250168
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Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10
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Biochemical Assay Reagents
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Others
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Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.
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-
- HY-W129593
-
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Sorbitan monostearate
|
Biochemical Assay Reagents
|
Others
|
|
Sorbitan monooctadecanoate is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can be used as an excipient, such as emulsifiers, nonionic surfactants, solubilizers, wetting and dispersing/suspending agents. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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-
- HY-W115818
-
|
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Biochemical Assay Reagents
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Others
|
|
Polyoxyethylene Sorbitan Monostearate is an ester of the saturated fatty acid stearic acid (C18:0). Polyoxyethylene Sorbitan Monostearate can be used as an excipient, such as surfactant, emulsifier, solubilizer, wetting agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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-
- HY-N0668
-
|
|
GLUT
Amylases
NF-κB
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
|
-
- HY-W250179
-
|
Polyoxyethylene (6) cetyl ether
|
Biochemical Assay Reagents
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Others
|
|
Hexaethylene glycol monohexadecyl ether, is a nonionic surfactant belonging to the polyethylene glycol (PEG) ether family. It has a hydrophilic head and a lipophilic tail, which makes it suitable for a wide range of applications. Specifically, Hexaethylene glycol monohexadecyl ether is commonly used in membrane protein research, for solubilization and stabilization of proteins, and for structural analysis techniques such as X-ray crystallography and electron microscopy. Additionally, Hexaethylene glycol monohexadecyl ether is used in a variety of other industrial and research applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Its unique properties make it ideal for facilitating interactions between molecules with different physicochemical properties.
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-
- HY-N0668R
-
|
|
GLUT
Amylases
NF-κB
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Rubusoside (Standard) is the analytical standard of Rubusoside. This product is intended for research and analytical applications. Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
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-
- HY-45072
-
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|
Biochemical Assay Reagents
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Others
|
|
Croscarmellose sodium is a commonly used pharmaceutical additive approved by the US Food and Drug Administration (FDA). Croscarmellose sodium is used in injectable preparations as a suspending agent to promote solubilization of compounds with poor water solubility. Croscarmellose sodium is also present in tablets as binder, glidant and antiadherent, in bulk laxatives as active principle and as an additive in food products. Croscarmellose sodium can be used as an excipient, such as excipients, disintegrants, aids in disintegration. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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-
| Cat. No. |
Product Name |
Type |
-
- HY-Y0537C
-
|
Potassium chloride, suitable for the extraction and solubilization of proteins
|
Buffer Reagents
|
|
Potassium chloride, ≥99.99% trace metals basis is a biochemical assay reagent suitable for protein extraction and solubilization.
|
-
- HY-D1005F
-
|
PEG-PPG-PEG, 2500(Average Mn)
|
Co-solvents
|
|
Poloxamer 182 (L62) can be used as an excipient, such as Emulsifier, solubilizer, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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-
- HY-116285
-
|
|
Enzyme Substrates
|
|
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .
|
-
- HY-Y0537B
-
|
|
Buffer Reagents
|
|
Potassium chloride, for molecular biology is a potassium chloride that can be used at the molecular level for protein extraction and solubilization.
|
-
- HY-Y0873P
-
|
Polyethylene glycol 10000
|
Co-solvents
|
|
PEG10000 (Polyethylene glycol 10000) can be used as a solubilizer. PEG10000 is a kind of biological materials or organic compounds that are widely used in life science research .
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-
- HY-136962
-
|
Amidosulfobetaine-14
|
Surfactants
|
|
ASB-14 (Amidosulfobetaine-14) is a zwitterionic amidosulfobetaine surfactant with membrane protein solubilizing. ASB-14 can be used for the preparative extraction and solubilization of proteins .
|
-
- HY-W127401
-
|
n-Octyltrioxyethylene
|
Biochemical Assay Reagents
|
|
Triethylene glycol monooctyl ether is a surfactant, C8E3 solubilizes membrane proteins.
|
-
- HY-166519
-
|
α‐HPCD (MW 1180)
|
Co-solvents
|
|
(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) is a cyclic oligosaccharide derivative that acts as a solubilizer in various experiments.
|
-
- HY-W250172
-
|
|
Surfactants
|
|
Triton X-405 is a nonionic surfactant commonly used in a variety of industrial and research applications. Triton X-405 belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in emulsions, detergents and solubilizers. Triton X-405 is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. It is also used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Additionally, Triton X-405 is used in the production of microemulsions, salves and lotions due to its emulsifying and solubilizing properties. However, it can be toxic if ingested or inhaled, so proper handling and safety precautions are required.
|
-
- HY-B1620D
-
|
PVP K25; Polyvidone K25; Povidone K25
|
Thickeners
|
|
Polyvinylpyrrolidone K25 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K25 can be used as stabilizer, emulsifier, suspension agent, solubilizer, protective colloid and complexing agent .
|
-
- HY-B1620E
-
|
PVP K60; Polyvidone K60; Povidone K60
|
Thickeners
|
|
Polyvinylpyrrolidone K60 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K60 can be used as stabilizer, emulsifier, suspension agent, solubilizer, protective colloid and complexing agent .
|
-
- HY-158083
-
|
|
Drug Delivery
|
|
Polymethacrylate Copolymer forms nanodiscs spontaneously by fragmentation or solubilization of the lipid bilayers.Polymethacrylate Copolymer is used in designing of nanodisc-forming polymer to mimic the amphiphilic nature of proteins and peptides .
|
-
- HY-15435A
-
|
|
Surfactants
|
|
CHAPS hydrate, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution .
|
-
- HY-Y0873Q
-
|
Polyethylene glycol 20000
|
Co-solvents
|
|
PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria .
|
-
- HY-W250178
-
|
|
Biochemical Assay Reagents
|
|
Octaethylene glycol monodecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monodecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monodecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.
|
-
- HY-W250195
-
|
|
Biochemical Assay Reagents
|
|
Hexaethylene glycol monotetradecyl ether is a kind of nonionic surfactant with hydrophilic head and lipophilic tail. It belongs to the class of polyethylene glycol (PEG) ethers and is widely used in different industrial and research applications. Due to its unique properties, Hexaethylene glycol monotetradecyl ether is commonly used in lotions, detergents and solubilizers. It is particularly useful in the study of membrane proteins and can be used to stabilize and solubilize proteins for use in structural analysis techniques. Due to its moisturizing and emulsifying properties, Hexaethylene glycol monotetradecyl ether is also used in personal care and cosmetics.
|
-
- HY-W250176
-
|
|
Biochemical Assay Reagents
|
|
Polyethylene glycol trimethylnonyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Polyethylene glycol trimethylnonyl ether is particularly useful in protein chemistry, where it is used to solubilize and stabilize proteins, such as membrane proteins, for structural analysis techniques. In addition, Polyethylene glycol trimethylnonyl ether has potential applications in drug delivery and other medical fields due to its ability to interact with and penetrate cell membranes.
|
-
- HY-W040224
-
|
|
Surfactants
|
|
Octyl β-D-thioglucopyranoside is a non-ionic detergent that can be used in the field of membrane biochemistry. Octyl β-D-thioglucopyranoside has the ability to solubilize E. coli membrane proteins .
|
-
- HY-W099581
-
|
SB3-14; DMAPS
|
Surfactants
|
|
Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
|
-
- HY-W250171
-
|
Polyoxyethylene (10) cetyl ether
|
Biochemical Assay Reagents
|
|
Octaethylene glycol monohexadecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. Octaethylene glycol monohexadecyl ether belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail, suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monohexadecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monohexadecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.
|
-
- HY-157883
-
|
Dimethyl-2-hydroxyethylampropanepropanesulfonate
|
Surfactants
|
|
C7BzO (Dimethyl-2-hydroxyethylampropanepropanesulfonate) is a potent solubilizing detergent that can be used for samples such as bacteria, mammals, and plants. C7BzO can be used for the extraction of proteins and the preparation of two-dimensional gel electrophoresis samples .
|
-
- HY-W099581R
-
|
|
Surfactants
|
|
Sulfobetaine-14 (Standard) is the analytical standard of Sulfobetaine-14. This product is intended for research and analytical applications. Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
|
-
- HY-W440898
-
|
|
Drug Delivery
|
|
DSPE-PEG-SH, MW 5000 is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide. Reagent grade, for research use only.
|
-
- HY-126403
-
|
PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated
|
Co-solvents
|
|
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .
|
-
- HY-W127627
-
|
|
Co-solvents
|
|
Tween 85 is a nonionic surfactant belonging to the class of ethoxylated sorbitan esters. It is used as an emulsifier and solubilizer in various industries such as pharmaceutical, cosmetic and food. Because of its ability to blend oily and water-based ingredients, Tween 85 is often used in the formulation of creams, lotions and ointments. In addition, it is used as a dispersant for pigments in the production of paints and coatings.
|
-
- HY-134924
-
|
|
Co-solvents
|
|
Succinyl-β-cycloaltrin is a modified cyclodextrin with unique chemical properties that make it an effective solubilizer and stabilizer for various compounds, especially in the pharmaceutical industry. Succinyl-β-cycloaltrin has a hydrophobic interior and a hydrophilic exterior, enabling it to form stable clathrates with hydrophobic molecules such as drugs and nutrients. This increases their solubility and bioavailability, making them more effective for recreational or nutritional purposes.
|
-
- HY-101461
-
|
Methyl-beta-cyclodextrin
|
Co-solvents
|
|
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .
|
-
- HY-W013076
-
|
tetra(decyl)ammonium bromide
|
Surfactants
|
|
Tetrakis(decyl)ammonium bromide is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrakis(decyl)ammonium bromide is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, cleansers and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, facilitating the movement of reactants between immiscible phases.
|
-
- HY-W099575
-
|
|
Surfactants
|
|
3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.
|
-
- HY-W440901
-
|
|
Drug Delivery
|
|
DSPE-PEG-SPDP, MW 5000 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond. Reagent grade, for research use only.
|
-
- HY-W142692
-
|
|
Surfactants
|
|
Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration .
|
-
- HY-137234
-
|
2,6-Di-O-methyl-β-cyclodextrin
|
Co-solvents
|
|
DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
|
-
- HY-W008974
-
|
|
Surfactants
|
|
3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA.
|
-
- HY-W250166
-
|
|
Biochemical Assay Reagents
|
|
Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.
|
-
- HY-W250181
-
|
Octyl β-D-thiomaltopyranoside
|
Biochemical Assay Reagents
|
|
Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.
|
-
- HY-W250168
-
|
Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10
|
Surfactants
|
|
Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.
|
-
- HY-W250179
-
|
Polyoxyethylene (6) cetyl ether
|
Biochemical Assay Reagents
|
|
Hexaethylene glycol monohexadecyl ether, is a nonionic surfactant belonging to the polyethylene glycol (PEG) ether family. It has a hydrophilic head and a lipophilic tail, which makes it suitable for a wide range of applications. Specifically, Hexaethylene glycol monohexadecyl ether is commonly used in membrane protein research, for solubilization and stabilization of proteins, and for structural analysis techniques such as X-ray crystallography and electron microscopy. Additionally, Hexaethylene glycol monohexadecyl ether is used in a variety of other industrial and research applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Its unique properties make it ideal for facilitating interactions between molecules with different physicochemical properties.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W250166
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.
|
-
- HY-P5878
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
RG33 Peptide is a diabetes inhibitor that significantly improves glucose clearance in insulin-resistant mice. RG33 Peptide effectively solubilizes lipid vesicles and promotes cholesterol efflux in cultured macrophages. RG33 Peptide is used in research into type 2 diabetes (T2D) .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-135737
-
-
-
- HY-N0668
-
-
-
- HY-N0668R
-
|
|
Structural Classification
other families
Terpenoids
Source classification
Diterpenoids
Plants
|
GLUT
Amylases
NF-κB
|
|
Rubusoside (Standard) is the analytical standard of Rubusoside. This product is intended for research and analytical applications. Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N2334S
-
|
|
|
Glycochenodeoxycholic acid-d4 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2].
|
-
-
- HY-N2334AS
-
|
|
|
Glycochenodeoxycholic acid-d7 (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].
|
-
-
- HY-116285S1
-
|
|
|
1-O-n-Octyl-β-D-glucopyranoside-d17 is the deuterium labeled n-Octyl β-D-glucopyranoside[1]. n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins[2][3].
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-151787
-
|
|
|
Azide
|
|
Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151786
-
|
|
|
Alkynes
Azide
|
|
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-D1005F
-
|
PEG-PPG-PEG, 2500(Average Mn)
|
|
Emulsifiers
Surfactants
|
|
Poloxamer 182 (L62) can be used as an excipient, such as Emulsifier, solubilizer, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-126403
-
|
PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated
|
|
Thickeners
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Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .
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- HY-101530C
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PEG 100 stearate
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Emulsifiers
Bases
Solubilizing Agents
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Polyoxyl 100 stearate can be used as an excipient, such as o/w emulsifiers, solubilizers, ointment and suppository bases. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-W129593
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Sorbitan monostearate
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Emulsifiers
Solubilizing Agents
Surfactants
Suspending Agents
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Sorbitan monooctadecanoate is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can be used as an excipient, such as emulsifiers, nonionic surfactants, solubilizers, wetting and dispersing/suspending agents. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-45072
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Disintegrants
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Croscarmellose sodium is a commonly used pharmaceutical additive approved by the US Food and Drug Administration (FDA). Croscarmellose sodium is used in injectable preparations as a suspending agent to promote solubilization of compounds with poor water solubility. Croscarmellose sodium is also present in tablets as binder, glidant and antiadherent, in bulk laxatives as active principle and as an additive in food products. Croscarmellose sodium can be used as an excipient, such as excipients, disintegrants, aids in disintegration. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-154637
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Emulsifiers
Solubilizing Agents
Surfactants
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Sucrose Stearate can be used as an excipient, such as Surfactants, emulsifiers, solubilizers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-154639
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Emulsifiers
Solubilizing Agents
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Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-154630
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Solubilizing Agents
Surfactants
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Polyoxypropylene stearyl ether can be used as an excipient, such as surfactant, softener, lubricating, wetting, plasticizing, solubilizing and dispersing properties. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-W115818
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Emulsifiers
Solubilizing Agents
Surfactants
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Polyoxyethylene Sorbitan Monostearate is an ester of the saturated fatty acid stearic acid (C18:0). Polyoxyethylene Sorbitan Monostearate can be used as an excipient, such as surfactant, emulsifier, solubilizer, wetting agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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