2. Immunology/Inflammation
  3. Nuclear Factor of activated T Cells (NFAT) CD3 CD28 Interleukin Related
  4. UR-1505

UR-1505 is a nuclear factor of activated T cells (NF-AT) inhibitor. UR-1505 can suppress CD3/CD28 induced T cell proliferation, increase p27KIP levels, and induce G1/S cell cycle arrest. UR-1505 can also inhibit the production of IL-5 and IFN-γ in activated T cells. UR-1505 has immunomodulatory properties and can be used in the study of atopic dermatitis.

For research use only. We do not sell to patients.

UR-1505 Chemical Structure

UR-1505 Chemical Structure

CAS No. : 651331-92-9

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UR-1505 Related Antibodies

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

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Description

UR-1505 is a nuclear factor of activated T cells (NF-AT) inhibitor. UR-1505 can suppress CD3/CD28 induced T cell proliferation, increase p27KIP levels, and induce G1/S cell cycle arrest. UR-1505 can also inhibit the production of IL-5 and IFN-γ in activated T cells. UR-1505 has immunomodulatory properties and can be used in the study of atopic dermatitis[1].
Molecular Weight

286.15

Formula

C10H7F5O4
CAS No.
SMILES

O=C(C1=CC=C(C=C1O)OCC(F)(C(F)(F)F)F)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UR-1505 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UR-1505651331-92-9UR1505UR 1505Nuclear Factor of activated T Cells (NFAT)CD3CD28Interleukin RelatedCluster of differentiation 3ILnuclear factor of activated T cellsT cell proliferationIL-5IFN-γimmunomodulatoryInhibitorinhibitorinhibit

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