Zapoterin (Synonyms: 11β-Hydroxyobacunone)

Cat. No.: HY-N1052: FAQs
Data Sheet Handling Instructions

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Zapoterin (11β-Hydroxyobacunone) is a natural product.

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Zapoterin Chemical Structure

CAS No. : 23885-43-0

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Biological Activity
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Description

Zapoterin (11β-Hydroxyobacunone) is a natural product^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BGC-823	IC₅₀	> 10 μM Compound: 13	Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 24593150]
BV-2	IC₅₀	5.3 μM Compound: 13	Inhibition of LPS-induced NO production in mouse BV2 cells compound pre-treated for 1 hr before LPS addition measured after 24 hrs by Griess assay Inhibition of LPS-induced NO production in mouse BV2 cells compound pre-treated for 1 hr before LPS addition measured after 24 hrs by Griess assay	[PMID: 24593150]
HCT-116	IC₅₀	> 10 μM Compound: 13	Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay	[PMID: 24593150]
HepG2	IC₅₀	> 10 μM Compound: 13	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 24593150]
NCI-H1650	IC₅₀	> 10 μM Compound: 13	Cytotoxicity against human NCI-H1650 cells after 96 hrs by MTT assay Cytotoxicity against human NCI-H1650 cells after 96 hrs by MTT assay	[PMID: 24593150]
SK-OV-3	IC₅₀	> 10 μM Compound: 13	Cytotoxicity against human SKOV3 cells after 96 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 96 hrs by MTT assay	[PMID: 24593150]

Molecular Weight

470.51

Formula

C₂₆H₃₀O₈

CAS No.

23885-43-0

SMILES

C[C@]12[C@]34[C@](C(O[C@@H](C5=COC=C5)[C@@]4(C[C@@H]([C@]1([H])[C@@]6([C@@](C(C)(OC(C=C6)=O)C)([H])CC2=O)C)O)C)=O)([H])O3

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

Zapoterin Related Classifications

Others

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zapoterin23885-43-011β-HydroxyobacunoneOthersInhibitorinhibitorinhibit

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